Professor Juha Toyras
Professorial Research Fellow
School of Electrical Engineering & Computer Science
Juha Töyräs holds a position of Professorial Research Fellow in the School of Electrical Engineering and Computer Science, The University of Queensland. He is also is the Head of Research and Innovation, Kuopio University Hospital and Wellbeing Services County of North Savo, and Professor of Medical Physics and Engineering, University of Eastern Finland. He has a PhD degree in the field of medical physics and his research is focused on medical devices and sensors, medical imaging, medical signal processing and connective tissue biomechanics. Since 2004, he has been the Vice/Co-Head of the Biophysics of Bone and Cartilage research group and Co-Head of the Sleep Technology and Analytics group since it was founded in January 2017 at the Department of Applied Physics, University of Eastern Finland. The groups are relatively large (three professors, c.20 research fellows and postdocs and >50 PhD students) and productive (>500 full papers and >80 PhD theses during the last 20 years). Professor Töyräs holds research grants from various European and Australian sources.
He has published 319 peer-reviewed full scientific papers and numerous abstracts in international scientific meetings. In addition, he has completed supervision of 51 PhD students and number of MSc students. His papers have been cited over 13000 times and his Hirsch-index is 63 (Google Scholar). Currently, Professor Toyras supervises (University of Eastern Finland, The University of Queensland) c.20 PhD-students and number of research fellows in various fields of biomedical engineering.
In addition to scientific publications and supervised academic theses, his work has led to patents and commercialization of scientific innovations. One example of this line of research is the development of a forehead EEG-electrode set for emergency medicine. The Bittium BrainStatus EEG-electrode set is patented, CE-approved and currently in global market (https://www.bittium.com/products_services/medical/bittium_brainstatus
Researcher biography
Juha Töyräs holds a position of Professorial Research Fellow in the School of Information Technology and Electrical Engineering, The University of Queensland. He is also is the Head of Research and Innovation, Kuopio University Hospital and Wellbeing Services County of North Savo, and Professor of Medical Physics and Engineering, University of Eastern Finland. He has a PhD degree in the field of medical physics and his research is focused on medical devices and sensors, medical imaging, medical signal processing and connective tissue biomechanics. Since 2004, he has been the Vice/Co-Head of the Biophysics of Bone and Cartilage research group and Co-Head of the Sleep Technology and Analytics group since it was founded in January 2017 at the Department of Applied Physics, University of Eastern Finland. The groups are relatively large (three professors, c.20 research fellows and postdocs and >60 PhD students) and productive (>750 full papers and >80 PhD theses during the last 20 years). Professor Töyräs holds research grants from various European and Australian sources. He has published 323 peer-reviewed full scientific papers and numerous abstracts in international scientific meetings. In addition, he has completed supervision of 52 PhD students and number of MSc students. His papers have been cited over 14000 times and his Hirsch-index is 63 (Google Scholar). Currently, Professor Toyras supervises (University of Eastern Finland, The University of Queensland) c.20 PhD-students and number of research fellows in various fields of biomedical engineering. In addition to scientific publications and supervised academic theses, his work has led to patents and commercialization of scientific innovations. One example of this line of research is the development of a forehead EEG-electrode set for emergency medicine. The Bittium BrainStatus EEG-electrode set is patented, CE-approved and currently in global market (https://www.bittium.com/products_services/medical/bittium_brainstatus).
Book Chapters
Leppänen, Timo, Kainulainen, Samu, Korkalainen, Henri, Sillanmäki, Saara, Kulkas, Antti, Töyräs, Juha and Nikkonen, Sami (2023). Correction to: Pulse Oximetry: The Working Principle, Signal Formation, and Applications. Advances in the diagnosis and treatment of sleep apnea: filling the gap between physicians and engineers. (pp. C1-C1) edited by Thomas Penzel and Roberto Hornero. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-031-06413-5_23
Leppänen, Timo, Kainulainen, Samu, Korkalainen, Henri, Sillanmäki, Saara, Kulkas, Antti, Töyräs, Juha and Nikkonen, Sami (2022). Pulse oximetry: the working principle, signal formation, and applications. Advances in the diagnosis and treatment of sleep apnea: filling the gap between physicians and engineers. (pp. 205-218) edited by Thomas Penzel and Roberto Hornero. Singapore, Singapore: Springer Singapore. doi: 10.1007/978-3-031-06413-5_12
Karjalainen, Janne P., Riekkinen, Ossi, Töyräs, Juha and Jurvelin, Jukka S. (2011). Linear acoustics of trabecular bone. Bone Quantitative Ultrasound. (pp. 265-289) Dordrecht: Springer Netherlands. doi: 10.1007/978-94-007-0017-8_10
Journal Articles
Pitkänen, Minna, Pitkänen, Henna, Nath, Rajdeep Kumar, Nikkonen, Sami, Kainulainen, Samu, Korkalainen, Henri, Ólafsdóttir, Kristín Anna, Arnardottir, Erna Sif, Sigurdardottir, Sigridur, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Töyräs, Juha and Leppänen, Timo (2024). Temporal and sleep stage‐dependent agreement in manual scoring of respiratory events. Journal of Sleep Research. doi: 10.1111/jsr.14391
Rusanen, Matias, Jouan, Gabriel, Huttunen, Riku, Nikkonen, Sami, Sigurðardóttir, Sigríður, Töyräs, Juha, Duce, Brett, Myllymaa, Sami, Arnardottir, Erna Sif, Leppänen, Timo, Islind, Anna Sigridur, Kainulainen, Samu and Korkalainen, Henri (2024). Retrospective validation of automatic sleep analysis with grey areas model for human‐in‐the‐loop scoring approach. Journal of Sleep Research. doi: 10.1111/jsr.14362
Pitkänen, Minna, Huovinen, Juho, Rissanen, Marika, Pitkänen, Henna, Kainulainen, Samu, Penzel, Thomas, Fanfulla, Francesco, Anttalainen, Ulla, Saaresranta, Tarja, Grote, Ludger, Hedner, Jan, Staats, Richard, Duce, Brett, Töyräs, Juha, Oksenberg, Arie and Leppänen, Timo (2024). Arousal burden is highest in supine sleeping position and during light sleep. Journal of Clinical Sleep Medicine. doi: 10.5664/jcsm.11398
Esrafilian, Amir, Chandra, Shekhar S, Gatti, Anthony A, Nissi, Mikko, Mustonen, Anne-Mari, Saisanen, Laura, Reijonen, Jusa, Nieminen, Petteri, Julkunen, Petro, Toyras, Juha, Saxby, David J, Lloyd, David G and Korhonen, Rami K (2024). An automated and robust tool for musculoskeletal and finite element modeling of the knee joint. IEEE Transactions on Biomedical Engineering, 1-13. doi: 10.1109/tbme.2024.3438272
Khan, Bilour, Nippolainen, Ervin, Shahini, Fatemeh, Nonappa, , Popov, Alexey, Töyräs, Juha and Afara, Isaac O. (2024). Relationship between depth-wise refractive index and biomechanical properties of human articular cartilage. Journal of biomedical optics, 29 (9) 095003, 095003-095003. doi: 10.1117/1.JBO.29.9.095003
Mattison, Graeme, Canfell, Oliver J., Smith, Daniel, Forrester, Doug, Reid, David, Töyräs, Juha and Dobbins, Chelsea (2024). “An excellent servant but a terrible master”: understanding the value of wearables for self-management in people with cystic fibrosis and their healthcare providers – a qualitative study. International Journal of Medical Informatics, 189 105532, 105532. doi: 10.1016/j.ijmedinf.2024.105532
Krebs, P., Nägele, M., Fomina, P., Virtanen, V., Nippolainen, E., Shaikh, R., Afara, I.O., Töyräs, J., Usenov, I., Sakharova, T., Artyushenko, V., Tafintseva, V., Solheim, J.H., Zimmermann, B., Kohler, A., König, O., Saarakkala, S. and Mizaikoff, B. (2024). Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: Potential and challenges for diagnosing osteoarthritis. Osteoarthritis and Cartilage Open, 6 (2) 100466, 100466. doi: 10.1016/j.ocarto.2024.100466
Chen, Xin, Leppänen, Timo, Kainulainen, Samu, Howarth, Timothy P., Oksenberg, Arie, Töyräs, Juha, Terrill, Philip I. and Korkalainen, Henri (2024). Sleep stage continuity is associated with objective daytime sleepiness in patients with suspected obstructive sleep apnea. Journal of Clinical Sleep Medicine, 20 (10), 1595-1606. doi: 10.5664/jcsm.11198
Linus, Awuniji, Tanska, Petri, Nippolainen, Ervin, Tiitu, Virpi, Töyras, Juha, Korhonen, Rami K., Afara, Isaac O. and Mononen, Mika E. (2024). Site-specific elastic and viscoelastic biomechanical properties of healthy and osteoarthritic human knee joint articular cartilage. Journal of Biomechanics, 169 112135, 112135. doi: 10.1016/j.jbiomech.2024.112135
Pahari, Purbanka, Korkalainen, Henri, Karhu, Tuomas, Arnardottir, Erna Sif, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Reaction time in psychomotor vigilance task is related to hypoxic load in males with sleep apnea. Journal of Sleep Research, 33 (2) e13988. doi: 10.1111/jsr.13988
Staykov, Eric, Mann, Dwayne L., Duce, Brett, Kainulainen, Samu, Leppänen, Timo, Töyräs, Juha, Azarbarzin, Ali, Georgeson, Thomas, Sands, Scott A. and Terrill, Philip I. (2024). Increased flow limitation during sleep is associated with increased psychomotor vigilance task lapses in individuals with suspected obstructive sleep apnea. CHEST, 165 (4), 990-1003. doi: 10.1016/j.chest.2023.11.031
Pahari, Purbanka, Korkalainen, Henri, Arnardóttir, Erna Sif, Islind, Anna Sigridur, August, Elias, Oksenberg, Arie, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2024). Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxemia in sleep apnea patients. ERJ Open Research, 10 (4) 01051-2023, 01051-2023. doi: 10.1183/23120541.01051-2023
Ebrahimian, Serajeddin, Sillanmäki, Saara, Hietakoste, Salla, Kulkas, Antti, Töyräs, Juha, Bailon, Raquel, Hernando, David, Lombardi, Carolina, Grote, Ludger, Bonsignore, Maria R, Saaresranta, Tarja, Pépin, Jean-Louis, Leppänen, Timo and Kainulainen, Samu (2024). Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients. American Journal of Physiology-Heart and Circulatory Physiology, 326 (5), H1094-H1104. doi: 10.1152/ajpheart.00760.2023
Jäntti, Jiri, Joenathan, Anisha, Fugazzola, Maria, Tuppurainen, Juuso, Honkanen, Juuso T. J., Töyräs, Juha, van Weeren, René, Snyder, Brian D., Grinstaff, Mark W., Matikka, Hanna and Mäkelä, Janne T.A. (2024). Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations. Osteoarthritis and Cartilage, 32 (3), 299-309. doi: 10.1016/j.joca.2023.11.020
Orava, Heta, Paakkari, Petri, Jäntti, Jiri, Honkanen, Miitu K. M., Honkanen, Juuso T. J., Virén, Tuomas, Joenathan, Anisha, Tanska, Petri, Korhonen, Rami K., Grinstaff, Mark W., Töyräs, Juha and Mäkelä, Janne T. A. (2024). Triple contrast computed tomography reveals site‐specific biomechanical differences in the human knee joint—A proof of concept study. Journal of Orthopaedic Research, 42 (2), 415-424. doi: 10.1002/jor.25683
Luukinen, Mieli, Pitkänen, Henna, Leppänen, Timo, Töyräs, Juha, Islind, Anna Sigridur, Kainulainen, Samu and Korkalainen, Henri (2024). Variation in the Photoplethysmogram Response to Arousal from Sleep Depending on the Cause of Arousal and the Presence of Desaturation. IEEE Journal of Translational Engineering in Health and Medicine, 12, 1-1. doi: 10.1109/jtehm.2024.3349916
Hietakoste, Salla, Armañac-Julián, Pablo, Karhu, Tuomas, Bailón, Raquel, Sillanmäki, Saara, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2024). Acute cardiorespiratory coupling impairment in worsening sleep apnea-related intermittent hypoxemia. IEEE Transactions on Biomedical Engineering, 71 (1), 326-333. doi: 10.1109/tbme.2023.3300079
Kafian-Attari, I., Nippolainen, E., Bergmann, F., George, A., Paakkari, P., Mirhashemi, A., Foschum, F., Kienle, A., Toyras, J. and Afara, I. O. (2024). Estimation of Photon Path Length and Penetration Depth in Articular Cartilage Zonal Architecture over the Therapeutic Window. IEEE Transactions on Biomedical Engineering, PP (99), 1-11. doi: 10.1109/TBME.2024.3368012
Shahini, Fatemeh, Oskouei, Soroush, Nippolainen, Ervin, Mohammadi, Ali, Sarin, Jaakko K., Moller, Nikae C. R. te, Brommer, Harold, Shaikh, Rubina, Korhonen, Rami K., van Weeren, P. René, Töyräs, Juha and Afara, Isaac O. (2024). Infrared Spectroscopy Can Differentiate Between Cartilage Injury Models: Implication for Assessment of Cartilage Integrity. Annals of Biomedical Engineering, 52 (9), 2521-2533. doi: 10.1007/s10439-024-03540-x
Pitkänen, Minna, Nath, Rajdeep Kumar, Korkalainen, Henri, Nikkonen, Sami, Mahamid, Alaa, Oksenberg, Arie, Duce, Brett, Töyräs, Juha, Kainulainen, Samu and Leppänen, Timo (2023). Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index. Sleep Advances, 5 (1) zpad054, 1-9. doi: 10.1093/sleepadvances/zpad054
Kafian-Attari, Iman, Nippolainen, Ervin, Bergmann, Florian, George, Akuroma, Paakkari, Petri, Mirhashemi, Arash, Foschum, Florian, Kienle, Alwin, Töyräs, Juha and Afara, Isaac O. (2023). Broadband scattering properties of articular cartilage zones and their relationship with the heterogenous structure of articular cartilage extracellular matrix. Journal of biomedical optics, 28 (12) 125003, 1-16. doi: 10.1117/1.JBO.28.12.125003
Pala, Swetha, Hänninen, Nina E., Mohammadi, Ali, Ebrahimi, Mohammadhossein, te Moller, Nikae C. R., Brommer, Harold, René van Weeren, P., Mäkelä, Janne T. A., Korhonen, Rami K., Afara, Isaac O., Töyräs, Juha, Mikkonen, Santtu, Nissi, Mikko J. and Nykänen, Olli (2023). 3D T1 relaxation time measurements in an equine model of subtle post‐traumatic osteoarthritis using MB‐SWIFT. Journal of Orthopaedic Research, 41 (12), 2657-2666. doi: 10.1002/jor.25629
Korkalainen, Henri, Kainulainen, Samu, Islind, Anna Sigridur, Óskarsdóttir, María, Strassberger, Christian, Nikkonen, Sami, Töyräs, Juha, Kulkas, Antti, Grote, Ludger, Hedner, Jan, Sund, Reijo, Hrubos-Strom, Harald, Saavedra, Jose M., Ólafsdóttir, Kristín Anna, Ágústsson, Jón S., Terrill, Philip I., McNicholas, Walter T., Arnardóttir, Erna Sif, Leppänen, Timo and On behalf of SLEEP REVOLUTION (2023). Review and perspective on sleep-disordered breathing research and translation to clinics. Sleep Medicine Reviews, 73 101874, 1-12. doi: 10.1016/j.smrv.2023.101874
Khan, Bilour, Nippolainen, Ervin, Shahini, Fatemeh, Torniainen, Jari, Mikkonen, Santtu, Nonappa, Popov, Alexey, Töyräs, Juha and Afara, Isaac (2023). Refractive index of human articular cartilage varies with tissue structure and composition. Journal of the Optical Society of America A, 40 (12), 2205-2214. doi: 10.1364/josaa.498722
Rusanen, Matias, Korkalainen, Henri, Gretarsdottir, Heidur, Siilak, Tiina, Olafsdottir, Kristin Anna, Töyräs, Juha, Myllymaa, Sami, Arnardottir, Erna Sif, Leppänen, Timo and Kainulainen, Samu (2023). Self-applied somnography: technical feasibility of electroencephalography and electro-oculography signal characteristics in sleep staging of suspected sleep-disordered adults. Journal of Sleep Research, 33 (2) e13977, e13977. doi: 10.1111/jsr.13977
Howarth, Timothy P., Karhu, Tuomas, Kainulainen, Samu, Chen, Xin, Mahamid, Alaa, Töyräs, Juha and Leppänen, Timo (2023). Oxygen resaturation rate is significantly associated with objectively assessed excessive daytime sleepiness in suspected obstructive sleep apnoea patients. Sleep Medicine, 107, 171-178. doi: 10.1016/j.sleep.2023.04.027
Kafian-Attari, Iman, Nippolainen, Ervin, Bergmann, Florian, Mirhashemi, Arash, Pakkari, Petri, Foschum, Florian, Kienle, Alwin, Töyräs, Juha and Afara, Isaac (2023). Impact of experimental setup parameters on measurement of articular cartilage optical properties in the visible and short near-infrared spectral bands. Biomedical Optics Express, 14 (7), 3397-3412. doi: 10.1364/boe.488801
Shaikh, Rubina, Tafintseva, Valeria, Nippolainen, Ervin, Virtanen, Vesa, Solheim, Johanne, Zimmermann, Boris, Saarakkala, Simo, Töyräs, Juha, Kohler, Achim and Afara, Isaac O. (2023). Characterisation of cartilage damage via fusing mid-infrared, near-infrared, and Raman spectroscopic data. Journal of Personalized Medicine, 13 (7) 1036, 1036. doi: 10.3390/jpm13071036
Linus, Awuniji, Tanska, Petri, Sarin, Jaakko K., Nippolainen, Ervin, Tiitu, Virpi, Mäkelä, Janne. T. A., Töyräs, Juha, Korhonen, Rami K., Mononen, Mika E. and Afara, Isaac O. (2023). Visible and near-infrared spectroscopy enables differentiation of normal and early osteoarthritic human knee joint articular cartilage. Annals of Biomedical Engineering, 51 (10), 2245-2257. doi: 10.1007/s10439-023-03261-7
Shehata, Eslam, Nippolainen, Ervin, Shaikh, Rubina, Ronkainen, Ari-Petteri, Töyräs, Juha, Sarin, Jaakko K. and Afara, Isaac O. (2023). Raman spectroscopy and machine learning enables estimation of articular cartilage structural, compositional, and functional properties. Annals of Biomedical Engineering, 51 (10), 2301-2312. doi: 10.1007/s10439-023-03271-5
Pahari, Purbanka, Korkalainen, Henri, Karhu, Tuomas, Rissanen, Marika, Arnardottir, Erna Sif, Hrubos‐Strøm, Harald, Duce, Brett, Töyräs, Juha, Leppänen, Timo and Nikkonen, Sami (2023). Obstructive sleep apnea‐related intermittent hypoxaemia is associated with impaired vigilance. Journal of Sleep Research, 32 (3) e13803, 1-9. doi: 10.1111/jsr.13803
Reddy, Pillareddy Vamsheedhar and Reddy, Karri Ganesh (2023). A multi-objective based scheduling framework for effective resource utilization in cloud computing. IEEE Access, 11, 37178-37193. doi: 10.1109/access.2023.3266294
Somaskandhan, Pranavan, Leppänen, Timo, Terrill, Philip I., Sigurdardottir, Sigridur, Arnardottir, Erna Sif, Ólafsdóttir, Kristín A., Serwatko, Marta, Sigurðardóttir, Sigurveig Þ., Clausen, Michael, Töyräs, Juha and Korkalainen, Henri (2023). Deep learning-based algorithm accurately classifies sleep stages in preadolescent children with sleep-disordered breathing symptoms and age-matched controls. Frontiers in Neurology, 14 1162998, 1-12. doi: 10.3389/fneur.2023.1162998
Duce, Brett, Kulkas, Antti, Oksenberg, Arie, Töyräs, Juha and Hukins, Craig (2023). Power spectral analysis of the sleep electroencephalogram in positional obstructive sleep apnea. Sleep Medicine, 104, 83-89. doi: 10.1016/j.sleep.2023.02.021
Rissanen, Marika, Korkalainen, Henri, Duce, Brett, Sillanmaki, Saara, Pitkanen, Henna, Suni, Aaron, Nikkonen, Sami, Kulkas, Antti, Toyras, Juha, Leppanen, Timo and Kainulainen, Samu (2023). Obstructive sleep apnea patients with atrial arrhythmias suffer from prolonged recovery from desaturations. IEEE Transactions on Biomedical Engineering, 70 (7), 2122-2130. doi: 10.1109/tbme.2023.3236680
Rusanen, Matias, Myllymaa, Sami, Kalevo, Laura, Myllymaa, Katja, Töyräs, Juha, Leppänen, Timo and Kainulainen, Samu (2023). Corrections to “An In-Laboratory Comparison of FocusBand EEG Device and Textile Electrodes Against a Medical-Grade System and Wet Gel Electrodes”. IEEE Access, 11, 37164-37165. doi: 10.1109/access.2023.3263457
Rusanen, M., Huttunen, R., Korkalainen, H., Myllymaa, S., Toyras, J., Myllymaa, K., Sigurdardottir, S., Olafsdottir, K. A., Leppanen, T., Arnardottir, E. S. and Kainulainen, S. (2023). Generalizable deep learning-based sleep staging approach for ambulatory textile electrode headband recordings. IEEE Journal of Biomedical and Health Informatics, 27 (99), 1-12. doi: 10.1109/jbhi.2023.3240437
Karhu, Tuomas, Leppänen, Timo, Korkalainen, Henri, Myllymaa, Sami, Duce, Brett, Töyräs, Juha and Nikkonen, Sami (2022). Desaturation event scoring criteria affect the perceived severity of nocturnal hypoxic load. Sleep Medicine, 100, 479-486. doi: 10.1016/j.sleep.2022.09.024
Ebrahimian, Serajeddin, Sillanmäki, Saara, Hietakoste, Salla, Duce, Brett, Kulkas, Antti, Töyräs, Juha, Leppänen, Timo, Lipponen, Jukka A. and Kainulainen, Samu (2022). Inter-sleep stage variations in corrected QT interval differ between obstructive sleep apnea patients with and without stroke history. PLoS One, 17 (12) e0278520, 1-11. doi: 10.1371/journal.pone.0278520
Huttunen, Riku, Leppanen, Timo, Duce, Brett, Arnardottir, Erna S., Nikkonen, Sami, Myllymaa, Sami, Toyras, Juha and Korkalainen, Henri (2022). A comparison of signal combinations for deep learning-based simultaneous sleep staging and respiratory event detection. IEEE Transactions on Biomedical Engineering, PP (99), 1704-1714. doi: 10.1109/tbme.2022.3225268
Karhu, Tuomas, Leppänen, Timo, Töyräs, Juha, Oksenberg, Arie, Myllymaa, Sami and Nikkonen, Sami (2022). ABOSA – Freely available automatic blood oxygen saturation signal analysis software: structure and validation. Computer Methods and Programs in Biomedicine, 226 107120, 1-10. doi: 10.1016/j.cmpb.2022.107120
Hietakoste, Salla, Karhu, Tuomas, Sillanmäki, Saara, Bailón, Raquel, Penzel, Thomas, Töyräs, Juha, Leppänen, Timo, Myllymaa, Sami and Kainulainen, Samu (2022). Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response. ERJ Open Research, 8 (4) 1, 12-12. doi: 10.1183/23120541.00121-2022
Nikkonen, Sami, Korkalainen, Henri, Töyräs, Juha and Leppänen, Timo (2022). STAR sleep recording export software for automatic export and anonymization of sleep studies. Scientific Reports, 12 (1) 15859, 1-7. doi: 10.1038/s41598-022-19892-0
Bolcos, Paul O., Mononen, Mika E., Roach, Koren E., Tanaka, Matthew S., Suomalainen, Juha‐Sampo, Mikkonen, Santtu, Nissi, Mikko J., Töyräs, Juha, Link, Thomas M., Souza, Richard B., Majumdar, Sharmila, Ma, C. Benjamin, Li, Xiaojuan and Korhonen, Rami K (2022). Subject‐specific biomechanical analysis to estimate locations susceptible to osteoarthritis—finite element modeling and MRI follow‐up of ACL reconstructed patients. Journal of Orthopaedic Research, 40 (8), 1744-1755. doi: 10.1002/jor.25218
Arnardottir, Erna S., Islind, Anna Sigridur, Óskarsdóttir, María, Ólafsdóttir, Kristín A., August, Elias, Jónasdóttir, Lára, Hrubos-Strøm, Harald, Saavedra, Jose M., Grote, Ludger, Hedner, Jan, Höskuldsson, Sveinbjörn, Ágústsson, Jón Skírnir, Jóhannsdóttir, Kamilla Rún, McNicholas, Walter T., Pevernagie, Dirk, Sund, Reijo, Töyräs, Juha and Leppänen, Timo (2022). The Sleep Revolution project: the concept and objectives. Journal of Sleep Research, 31 (4) e13630, 1-8. doi: 10.1111/jsr.13630
Cui, Andy, Nippolainen, Ervin, Shaikh, Rubina, Torniainen, Jari, Ristaniemi, Aapo, Finnilä, Mikko, Korhonen, Rami K., Saarakkala, Simo, Herzog, Walter, Töyräs, Juha and Afara, Isaac O. (2022). Assessment of Ligament Viscoelastic Properties Using Raman Spectroscopy. Annals of Biomedical Engineering, 50 (9), 1134-1142. doi: 10.1007/s10439-022-02988-z
Mattison, Graeme, Canfell, Oliver, Forrester, Douglas, Dobbins, Chelsea, Smith, Daniel, Töyräs, Juha and Sullivan, Clair (2022). The influence of wearables on healthcare outcomes in chronic disease: a systematic review. Journal of Medical Internet Research, 24 (7) e36690, 1-40. doi: 10.2196/36690
Mohammadi, Ali, te Moller, Nikae C. R., Ebrahimi, Mohammadhossein, Plomp, Saskia, Brommer, Harold, van Weeren, P. René, Mäkelä, Janne T. A., Töyräs, Juha and Korhonen, Rami K. (2022). Site- and zone-dependent changes in proteoglycan content and biomechanical properties of bluntly and sharply grooved equine articular cartilage. Annals of Biomedical Engineering, 50 (12), 1-11. doi: 10.1007/s10439-022-02991-4
Kalevo, Laura, Miettinen, Tomi, Leino, Akseli, Westeren-Punnonen, Susanna, Sahlman, Johanna, Mervaala, Esa, Toyras, Juha, Leppanen, Timo, Myllymaa, Sami and Myllymaa, Katja (2022). Self-applied electrode set provides a clinically feasible solution enabling EEG recording in home sleep apnea testing. IEEE Access, 10, 60633-60642. doi: 10.1109/ACCESS.2022.3178189
Virtanen, V., Tafintseva, V., Shaikh, R., Nippolainen, E., Haas, J., Afara, I. O., Töyräs, J., Kröger, H., Solheim, J., Zimmermann, B., Kohler, A., Mizaikoff, B., Finnilä, M., Rieppo, L. and Saarakkala, S. (2022). Infrared spectroscopy is suitable for objective assessment of articular cartilage health. Osteoarthritis and Cartilage Open, 4 (2) 100250, 1-7. doi: 10.1016/j.ocarto.2022.100250
Sillanmäki, Saara, Lipponen, Jukka A., Korkalainen, Henri, Kulkas, Antti, Leppänen, Timo, Nikkonen, Sami, Töyräs, Juha, Duce, Brett, Suni, Aaron and Kainulainen, Samu (2022). QTc prolongation is associated with severe desaturations in stroke patients with sleep apnea. BMC Pulmonary Medicine, 22 (1) 204, 1-10. doi: 10.1186/s12890-022-01996-y
Pitkanen, Henna, Duce, Brett, Leppanen, Timo, Kainulainen, Samu, Kulkas, Antti, Myllymaa, Sami, Toyras, Juha and Korkalainen, Henri (2022). Gamma power of electroencephalogram arousal is modulated by respiratory event type and severity in obstructive sleep apnea. IEEE Transactions on Biomedical Engineering, 69 (4), 1417-1423. doi: 10.1109/tbme.2021.3118229
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Li, Mao, Venäläinen, Mikko S., Chandra, Shekhar S., Patel, Rushabh, Fripp, Jurgen, Engstrom, Craig, Korhonen, Rami K., Töyräs, Juha and Crozier, Stuart (2021). Discrete element and finite element methods provide similar estimations for hip joint contact mechanics during walking gait. Journal of Biomechanics, 115 110163, 1-11. doi: 10.1016/j.jbiomech.2020.110163
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Ristaniemi, Aapo, Regmi, Dristi, Mondal, Diponkor, Torniainen, Jari, Tanska, Petri, Stenroth, Lauri, Finnilä, Mikko A. J., Töyräs, Juha and Korhonen, Rami K. (2021). Structure, composition and fibril-reinforced poroviscoelastic properties of bovine knee ligaments and patellar tendon. Journal of the Royal Society. Interface, 18 (174) 20200737, 1-11. doi: 10.1098/rsif.2020.0737
Leino, Akseli, Nikkonen, Sami, Kainulainen, Samu, Korkalainen, Henri, Töyräs, Juha, Myllymaa, Sami, Leppänen, Timo, Ylä-Herttuala, Salla, Westeren-Punnonen, Susanna, Muraja-Murro, Anu, Jäkälä, Pekka, Mervaala, Esa and Myllymaa, Katja (2020). Neural network analysis of nocturnal SpO2 signal enables easy screening of sleep apnea in patients with acute cerebrovascular disease. Sleep Medicine, 79, 71-78. doi: 10.1016/j.sleep.2020.12.032
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Mohammadi, Ali, Myller, Katariina A. H., Tanska, Petri, Hirvasniemi, Jukka, Saarakkala, Simo, Töyräs, Juha, Korhonen, Rami K. and Mononen, Mika E. (2020). Rapid CT-based estimation of articular cartilage biomechanics in the knee joint without cartilage segmentation. Annals of Biomedical Engineering, 48 (12), 2965-2975. doi: 10.1007/s10439-020-02666-y
Kafian-Attari, Iman, Nippolainen, Ervin, Semenov, Dmitry, Hauta-Kasari, Markku, Töyräs, Juha and Afara, Isaac O. (2020). Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity. Biomedical Optics Express, 11 (11), 6480-6494. doi: 10.1364/BOE.402929
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Ala-Myllymäki, Juho, Paakkonen, Tommi, Joukainen, Antti, Kröger, Heikki, Lehenkari, Petri, Töyräs, Juha and Afara, Isaac O. (2020). Near-infrared spectroscopy for mapping of human meniscus biochemical constituents. Annals of Biomedical Engineering, 49 (1), 469-476. doi: 10.1007/s10439-020-02578-x
Korkalainen, Henri, Leppanen, Timo, Aakko, Juhani, Nikkonen, Sami, Kainulainen, Samu, Leino, Akseli, Duce, Brett, Afara, Isaac Oluwaseun, Myllymaa, Sami and Toyras, Juha (2020). Accurate deep learning-based sleep staging in a clinical population with suspected obstructive sleep apnea. IEEE Journal of Biomedical and Health Informatics, 24 (7) 8936942, 2073-2081. doi: 10.1109/JBHI.2019.2951346
Kulkas, Antti, Duce, Brett, Töyräs, Juha, Seppä, Juha and Leppänen, Timo (2020). Comparison of the effect of weight change, simulated computational continuous positive airway pressure treatment and positional therapy on severity of sleep apnea. Journal of Sleep Research, 30 (2) e13070, e13070. doi: 10.1111/jsr.13070
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Nikkonen, Sami, Korkalainen, Henri, Kainulainen, Samu, Myllymaa, Sami, Leino, Akseli, Kalevo, Laura, Oksenberg, Arie, Leppänen, Timo and Töyräs, Juha (2020). Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network. Sleep, 43 (12) zsaa106. doi: 10.1093/sleep/zsaa106
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Myller, Katariina Anna Henriikka, Korhonen, Rami, Töyräs, Juha, Tanska, Petri, Väänänen, Sami, Jurvelin, Jukka S, Saarakkala, Simo and Mononen, Mika E (2020). Clinical contrast-enhanced computed tomography with semiautomatic segmentation provides feasible input for computational models of the knee joint. Journal of Biomechanical Engineering, 142 (5) 051001. doi: 10.1115/1.4045279
Torniainen, Jari, Afara, Isaac O., Prakash, Mithilesh, Sarin, Jaakko K., Stenroth, Lauri and Töyräs, Juha (2020). Open-source python module for automated preprocessing of near infrared spectroscopic data. Analytica Chimica Acta, 1108, 1-9. doi: 10.1016/j.aca.2020.02.030
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Ristaniemi, A., Torniainen, J., Stenroth, L., Finnilä, M. A.J., Paakkonen, T., Töyräs, J. and Korhonen, R. K. (2020). Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties. Journal of the Mechanical Behavior of Biomedical Materials, 104 103639, 103639. doi: 10.1016/j.jmbbm.2020.103639
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Afara, Isaac O., Sarin, Jaakko K., Ojanen, Simo, Finnilä, Mikko A. J., Herzog, Walter, Saarakkala, Simo, Korhonen, Rami K. and Töyräs, Juha (2020). Machine learning classification of articular cartilage integrity using near infrared spectroscopy. Cellular and Molecular Bioengineering, 13 (3), 219-228. doi: 10.1007/s12195-020-00612-5
Kalevo, Laura, Myllymaa, Sami, Miettinen, Tomi, Leino, Akseli, Kainulainen, Samu, Korkalainen, Henri, Myllymaa, Katja, Toyras, Juha, Leppanen, Timo and Laitinen, Tiina (2020). Effect of sweating on electrode-skin contact impedances and artifacts in EEG recordings with various screen-printed Ag/Agcl electrodes. IEEE Access, 8 9017959, 50934-50943. doi: 10.1109/ACCESS.2020.2977172
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Duce, Brett, Kulkas, Antti, Töyräs, Juha, Terrill, Philip and Hukins, Craig (2020). Longer duration electroencephalogram arousals have a better relationship with impaired vigilance and health status in obstructive sleep apnoea. Sleep and Breathing, 25 (1), 263-270. doi: 10.1007/s11325-020-02110-4
Nippolainen, Ervin, Shaikh, Rubina, Virtanen, Vesa, Rieppo, Lassi, Saarakkala, Simo, Töyräs, Juha and Afara, Isaac O. (2020). Near infrared spectroscopy enables differentiation of mechanically and enzymatically induced cartilage injuries. Annals of Biomedical Engineering, 48 (9), 2343-2353. doi: 10.1007/s10439-020-02506-z
Stenroth, Lauri, Sefa, Sandra, Arokoski, Jari and Töyräs, Juha (2019). Does magnetic resonance imaging provide superior reliability for achilles and patellar tendon cross-sectional area measurements compared with ultrasound imaging?. Ultrasound in Medicine and Biology, 45 (12), 3186-3198. doi: 10.1016/j.ultrasmedbio.2019.08.001
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Honkanen, Miitu K. M., Saukko, Annina E. A., Turunen, Mikael J., Shaikh, Rubina, Prakash, Mithilesh, Lovric, Goran, Joukainen, Antti, Kroger, Heikki, Grinstaff, Mark W. and Toyras, Juha (2019). Synchrotron MicroCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition. Journal of Orthopaedic Research, 38 (3) jor.24479, 563-573. doi: 10.1002/jor.24479
Nikkonen, Sami, Afara, Isaac O., Leppänen, Timo and Töyräs, Juha (2019). Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea. Scientific Reports, 9 (1) 13200, 13200. doi: 10.1038/s41598-019-49330-7
Sarin, Jaakko K., Torniainen, Jari, Prakash, Mithilesh, Rieppo, Lassi, Afara, Isaac O. and Toyras, Juha (2019). Dataset on equine cartilage near infrared spectra, composition, and functional properties. Scientific Data, 6 (1) 164, 164. doi: 10.1038/s41597-019-0170y
Kainulainen, Samu, Töyräs, Juha, Oksenberg, Arie, Korkalainen, Henri, Sefa, Sandra, Kulkas, Antti and Leppänen, Timo (2019). Severity of desaturations reflects OSA-related daytime sleepiness better than AHI. Journal of Clinical Sleep Medicine, 15 (8), 1135-1142. doi: 10.5664/jcsm.7806
Miettinen, Tomi, Myllymaa, Katja, Muraja-Murro, Anu, Westeren-Punnonen, Susanna, Hukkanen, Taina, Töyräs, Juha, Lappalainen, Reijo, Mervaala, Esa, Sipilä, Kirsi and Myllymaa, Sami (2019). Polysomnographic scoring of sleep bruxism events is accurate even in the absence of video recording but unreliable with EMG-only setups. Sleep and Breathing, 24 (3), 893-904. doi: 10.1007/s11325-019-01915-2
Bolcos, Paul O., Mononen, Mika E., Tanaka, Matthew S., Yang, Mingrui, Suomalainen, Juha-Sampo, Nissi, Mikko J., Töyräs, Juha, Ma, Benjamin, Li, Xiaojuan and Korhonen, Rami K. (2019). Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1ρ and T2 imaging. Clinical Biomechanics, 79 104844, 104844. doi: 10.1016/j.clinbiomech.2019.08.004
Prakash, M., Joukainen, A., Torniainen, J., Honkanen, M. K.M., Rieppo, L., Afara, I. O., Kröger, H., Töyräs, J. and Sarin, J. K. (2019). Near-infrared spectroscopy enables quantitative evaluation of human cartilage biomechanical properties during arthroscopy. Osteoarthritis and Cartilage, 27 (8), 1235-1243. doi: 10.1016/j.joca.2019.04.008
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Husso, Minna, Nissi, Mikko J., Kuivanen, Antti, Halonen, Paavo, Tarkia, Miikka, Teuho, Jarmo, Saunavaara, Virva, Vainio, Pauli, Sipola, Petri, Manninen, Hannu, Ylä-Herttuala, Seppo, Knuuti, Juhani and Toÿräs, Juha (2019). Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference. BMC Medical Imaging, 19 (1) 58, 58. doi: 10.1186/s12880-019-0359-8
Oksenberg, Arie, Gadoth, Natan, Töyräs, Juha and Leppänen, Timo (2019). Prevalence and characteristics of positional obstructive sleep apnea (POSA) in patients with severe OSA. Sleep and Breathing, 24 (2), 551-559. doi: 10.1007/s11325-019-01897-1
Nikkonen, Sami, Töyräs, Juha, Mervaala, Esa, Myllymaa, Sami, Terrill, Philip and Leppänen, Timo (2019). Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea. Sleep and Breathing, 24 (1), 379-386. doi: 10.1007/s11325-019-01885-5
Nykänen, O., Sarin, J. K., Ketola, J. H., Leskinen, H., te Moller, N. C.R., Tiitu, V., Mancini, I. A.D., Visser, J., Brommer, H., van Weeren, P. R., Malda, J., Töyräs, J. and Nissi, M. J. (2019). T2* and quantitative susceptibility mapping in an equine model of post-traumatic osteoarthritis: assessment of mechanical and structural properties of articular cartilage. Osteoarthritis and Cartilage, 27 (10), 1481-1490. doi: 10.1016/j.joca.2019.06.009
Saukko, Annina E. A., Turunen, Mikael J., Honkanen, Miitu K. M., Lovric, Goran, Tiitu, Virpi, Honkanen, Juuso T. J., Grinstaff, Mark W., Jurvelin, Jukka S. and Töyräs, Juha (2019). Simultaneous quantitation of cationic and non-ionic contrast agents in articular cartilage using synchrotron MicroCT imaging. Scientific Reports, 9 (1) 7118, 7118. doi: 10.1038/s41598-019-43276-6
Leppänen, Timo, Kulkas, Antti and Töyräs, Juha (2019). The hypoxic burden: also known as the desaturation severity parameter. European Heart Journal, 40 (35), 2991-2993. doi: 10.1093/eurheartj/ehz271
Honkanen, Miitu K. M., Matikka, Hanna, Honkanen, Juuso T. J., Bhattarai, Abhisek, Grinstaff, Mark W., Joukainen, Antti, Kröger, Heikki, Jurvelin, Jukka S. and Töyräs, Juha (2019). Imaging of proteoglycan and water contents in human articular cartilage with full-body CT using dual contrast technique. Journal of Orthopaedic Research, 37 (5) jor.24256, 1059-1070. doi: 10.1002/jor.24256
Myller, Katariina A. H., Korhonen, Rami K., Töyräs, Juha, Salo, Jari, Jurvelin, Jukka S. and Venäläinen, Mikko S. (2019). Computational evaluation of altered biomechanics related to articular cartilage lesions observed in vivo. Journal of Orthopaedic Research, 37 (5) jor.24273, 1042-1051. doi: 10.1002/jor.24273
Venäläinen, Mikko S., Mononen, Mika E., Salo, Jari, Räsänen, Lasse P., Jurvelin, Jukka S., Töyräs, Juha, Virén, Tuomas and Korhonen, Rami K. (2019). Publisher Correction: Quantitative evaluation of the mechanical risks caused by focal cartilage defects in the knee (Scientific Reports, (2016), 6, 1, (37538), 10.1038/srep37538). Scientific Reports, 9 (1) 5660, 5660. doi: 10.1038/s41598-019-41384-x
Leppänen, Timo, Kulkas, Antti, Mervaala, Esa and Töyräs, Juha (2019). Increase in body mass index decreases duration of apneas and hypopneas in obstructive sleep apnea. Respiratory Care, 64 (1), 77-84. doi: 10.4187/respcare.06297
Torniainen, Jari, Ristaniemi, Aapo, Sarin, Jaakko K., Mikkonen, Santtu, Afara, Isaac O., Stenroth, Lauri, Korhonen, Rami K. and Töyräs, Juha (2019). Near infrared spectroscopic evaluation of ligament and tendon biomechanical properties. Annals of Biomedical Engineering, 47 (1), 213-222. doi: 10.1007/s10439-018-02125-9
Kalevo, Laura, Miettinen, Tomi, Leino, Akseli, Kainulainen, Samu, Myllymaa, Katja, Toyras, Juha, Leppanen, Timo and Myllymaa, Sami (2019). Improved sweat artifact tolerance of screen-printed EEG electrodes by material selection-comparison of electrochemical properties in artificial sweat. IEEE Access, 7 8835030, 133237-133247. doi: 10.1109/ACCESS.2019.2941052
Nykänen, Olli, Rieppo, Lassi, Töyräs, Juha, Kolehmainen, Ville, Saarakkala, Simo, Shmueli, Karin and Nissi, Mikko J. (2018). Quantitative susceptibility mapping of articular cartilage: ex vivo findings at multiple orientations and following different degradation treatments. Magnetic Resonance in Medicine, 80 (6), 2702-2716. doi: 10.1002/mrm.27216
Bolcos, Paul O., Mononen, Mika E., Mohammadi, Ali, Ebrahimi, Mohammadhossein, Tanaka, Matthew S., Samaan, Michael A., Souza, Richard B., Li, Xiaojuan, Suomalainen, Juha-Sampo, Jurvelin, Jukka S., Töyräs, Juha and Korhonen, Rami K. (2018). Comparison between kinetic and kinetic-kinematic driven knee joint finite element models. Scientific Reports, 8 (1) 17351, 17351. doi: 10.1038/s41598-018-35628-5
Prakash, M., Sarin, J. K., Rieppo, L., Afara, I. O. and Töyräs, J. (2018). Accounting for spatial dependency in multivariate spectroscopic data. Chemometrics and Intelligent Laboratory Systems, 182, 166-171. doi: 10.1016/j.chemolab.2018.09.010
Myller, Katariina A. H., Honkanen, Juuso T. J., Jurvelin, Jukka S., Saarakkala, Simo, Töyräs, Juha and Väänänen, Sami P. (2018). Method for segmentation of knee articular cartilages based on contrast-enhanced CT images. Annals of Biomedical Engineering, 46 (11), 1756-1767. doi: 10.1007/s10439-018-2081-z
Leppänen, Timo, Kulkas, Antti, Oksenberg, Arie, Duce, Brett, Mervaala, Esa and Töyräs, Juha (2018). Differences in arousal probability and duration after apnea and hypopnea events in adult obstructive sleep apnea patients. Physiological Measurement, 39 (11) 114004, 114004. doi: 10.1088/1361-6579/aae42c
Kulkas, Antti, Leppanen, Timo, Kon, Sami Nik, Oksenberg, Arie, Duce, Brett, Mervaala, Esa and Toyras, Juha (2018). Required CPAP usage time to normalize AHI in obstructive sleep apnea patients: a simulation study. Physiological Measurement, 39 (11) 115009, 115009. doi: 10.1088/1361-6579/aae7fe
Ryynänen, Olli-Pekka, Leppänen, Timo, Kekolahti, Pekka, Mervaala, Esa and Töyräs, Juha (2018). Bayesian network model to evaluate the effectiveness of continuous positive airway pressure treatment of sleep apnea. Healthcare Informatics Research, 24 (4), 346-358. doi: 10.4258/hir.2018.24.4.346
Pouran, Behdad, Arbabi, Vahid, Bajpayee, Ambika G., van Tiel, Jasper, Töyräs, Juha, Jurvelin, Jukka S., Malda, Jos, Zadpoor, Amir A. and Weinans, Harrie (2018). Multi-scale imaging techniques to investigate solute transport across articular cartilage. Journal of Biomechanics, 78, 10-20. doi: 10.1016/j.jbiomech.2018.06.012
Sarin, Jaakko K., te Moller, Nikae C. R., Mancini, Irina A. D., Brommer, Harold, Visser, Jetze, Malda, Jos, van Weeren, P. René, Afara, Isaac O. and Töyräs, Juha (2018). Arthroscopic near infrared spectroscopy enables simultaneous quantitative evaluation of articular cartilage and subchondral bone in vivo. Scientific Reports, 8 (1) 13409, 13409. doi: 10.1038/s41598-018-31670-5
Miettinen, Tomi, Myllymaa, Katja, Hukkanen, Taina, Töyräs, Juha, Sipilä, Kirsi and Myllymaa, Sami (2018). Home polysomnography reveals a first-night effect in patients with low sleep bruxism activity. Journal of Clinical Sleep Medicine, 14 (8), 1377-1386. doi: 10.5664/jcsm.7278
Afara, Isaac O., Florea, Cristina, Olumegbon, Ismail A., Eneh, Chibuzor T., Malo, Markus K. H., Korhonen, Rami K. and Töyräs, Juha (2018). Characterizing human subchondral bone properties using near-infrared (NIR) spectroscopy. Scientific Reports, 8 (1) 9733, 9733. doi: 10.1038/s41598-018-27786-3
Lasanen, Roope, Malo, Markus K.H., Airaksinen, Olavi, Karhu, Jari, Töyräs, Juha and Julkunen, Petro (2018). Infrared thermography reveals effect of working posture on skin temperature in office workers. International Journal of Occupational Safety and Ergonomics, 24 (3), 457-463. doi: 10.1080/10803548.2017.1336299
Bhattarai, Abhisek, Honkanen, Juuso T. J., Myller, Katariina A. H., Prakash, Mithilesh, Korhonen, Miitu, Saukko, Annina E. A., Virén, Tuomas, Joukainen, Antti, Patwa, Amit N., Kröger, Heikki, Grinstaff, Mark W., Jurvelin, Jukka S. and Töyräs, Juha (2018). Quantitative dual contrast CT technique for evaluation of articular cartilage properties. Annals of Biomedical Engineering, 46 (7), 1038-1046. doi: 10.1007/s10439-018-2013-y
Miettinen, Tomi, Myllymaa, Katja, Westeren-Punnonen, Susanna, Ahlberg, Jari, Hukkanen, Taina, Toyras, Juha, Lappalainen, Reijo, Mervaala, Esa, Sipila, Kirsi and Myllymaa, Sami (2018). Success rate and technical quality of home polysomnography with self-applicable electrode set in subjects with possible sleep bruxism. IEEE Journal of Biomedical and Health Informatics, 22 (4), 1124-1132. doi: 10.1109/JBHI.2017.2741522
Duce, Brett, Kulkas, Antti, Langton, Christian, Töyräs, Juha and Hukins, Craig (2018). The prevalence of REM-related obstructive sleep apnoea is reduced by the AASM 2012 hypopnoea criteria. Sleep and Breathing, 22 (1), 57-64. doi: 10.1007/s11325-017-1526-1
Miettinen, Tomi, Myllymaa, Katja, Muraja-Murro, Anu, Westeren-Punnonen, Susanna, Hukkanen, Taina, Töyräs, Juha, Lappalainen, Reijo, Mervaala, Esa, Sipilä, Kirsi and Myllymaa, Sami (2018). Screen-printed ambulatory electrode set enables accurate diagnostics of sleep bruxism. Journal of Sleep Research, 27 (1), 103-112. doi: 10.1111/jsr.12536
Ala-Myllymäki, Juho, Danso, Elvis K., Honkanen, Juuso T. J., Korhonen, Rami K., Toÿräs, Juha and Afara, Isaac O. (2017). Optical spectroscopic characterization of human meniscus biomechanical properties. Journal of Biomedical Optics, 22 (12) 125008, 1. doi: 10.1117/1.JBO.22.12.125008
Ojanen, X., Tanska, P., Malo, M. K. H., Isaksson, H., Väänänen, S. P., Koistinen, A. P., Grassi, L., Magnusson, S. P., Ribel-Madsen, S. M., Korhonen, R. K., Jurvelin, J. S. and Töyräs, J. (2017). Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone – an experimental and finite element study. Journal of Biomechanics, 65, 96-105. doi: 10.1016/j.jbiomech.2017.10.002
Saukko, Annina E. A., Honkanen, Juuso T. J., Xu, Wujun, Väänänen, Sami P., Jurvelin, Jukka S., Lehto, Vesa-Pekka and Töyräs, Juha (2017). Dual contrast CT method enables diagnostics of cartilage injuries and degeneration using a single CT image. Annals of Biomedical Engineering, 45 (12), 2857-2866. doi: 10.1007/s10439-017-1916-3
Kulkas, Antti, Duce, Brett, Leppänen, Timo, Hukins, Craig and Töyräs, Juha (2017). Severity of desaturation events differs between hypopnea and obstructive apnea events and is modulated by their duration in obstructive sleep apnea. Sleep and Breathing, 21 (4), 829-835. doi: 10.1007/s11325-017-1513-6
Stewart, Rachel C., Honkanen, Juuso T.J., Kokkonen, Harri T., Tiitu, Virpi, Saarakkala, Simo, Joukainen, Antti, Snyder, Brian D., Jurvelin, Jukka S., Grinstaff, Mark W. and Töyräs, Juha (2017). Contrast-enhanced computed tomography enables quantitative evaluation of tissue properties at intrajoint regions in cadaveric knee cartilage. Cartilage, 8 (4), 391-399. doi: 10.1177/1947603516665443
Prakash, Mithilesh, Sarin, Jaakko K., Rieppo, Lassi, Afara, Isaac O. and Töyräs, Juha (2017). Optimal regression method for near-infrared spectroscopic evaluation of articular cartilage. Applied Spectroscopy, 71 (10), 2253-2262. doi: 10.1177/0003702817726766
Sarin, Jaakko K., Rieppo, Lassi, Brommer, Harold, Afara, Isaac O., Saarakkala, Simo and Töyräs, Juha (2017). Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure. Scientific Reports, 7 (1) 10586, 10586. doi: 10.1038/s41598-017-10973-z
Muraja-Murro, Anu, Nieminen, Outi, Julkunen, Petro, Töyräs, Juha, Laitinen, Tomi and Mervaala, Esa (2017). Peri-apneic hemodynamic reactions in obstructive sleep apnea. Pathophysiology, 24 (3), 197-203. doi: 10.1016/j.pathophys.2017.05.003
Viren, Tuomas, Honkanen, Juuso T., Danso, Elvis K., Rieppo, Lassi, Korhonen, Rami K. and Töyräs, Juha (2017). Ultrasound assessment of human meniscus. Ultrasound in Medicine and Biology, 43 (9), 1753-1763. doi: 10.1016/j.ultrasmedbio.2017.01.020
Leppänen, Timo, Töyräs, Juha, Mervaala, Esa, Penzel, Thomas and Kulkas, Antti (2017). Severity of individual obstruction events increases with age in patients with obstructive sleep apnea. Sleep Medicine, 37, 32-37. doi: 10.1016/j.sleep.2017.06.004
Sarin, J. K., Brommer, H., Argüelles, D., Puhakka, P. H., Inkinen, S. I., Afara, I. O., Saarakkala, S. and Töyräs, J. (2017). Corrigendum to “Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo” [Osteoarthritis Cartilage 25 (5) (2017 May) 790–798] (S1063458416304666), (10.1016/j.joca.2016.12.007)). Osteoarthritis and Cartilage, 25 (8), 1377-1378. doi: 10.1016/j.joca.2017.05.010
Joukainen, Antti, Virén, Tuomas, Penttilä, Pekko, Liukkonen, Jukka, Puhakka, Pia Henriikka, Kröger, Heikki and Töyräs, Juha (2017). Ultrasound arthroscopy of hip in treatment of osteochondritis dissecans. Arthroscopy Techniques, 6 (4), e1063-e1068. doi: 10.1016/j.eats.2017.03.022
Kulkas, Antti, Duce, Brett, Leppänen, Timo, Hukins, Craig and Töyräs, Juha (2017). Gender differences in severity of desaturation events following hypopnea and obstructive apnea events in adults during sleep. Physiological Measurement, 38 (8), 1490-1502. doi: 10.1088/1361-6579/aa7b6f
te Moller, N. C.R., Pitkänen, M., Sarin, J. K., Väänänen, S., Liukkonen, J., Afara, I. O., Puhakka, P. H., Brommer, H., Niemelä, T., Tulamo, R. M., Argüelles Capilla, D. and Töyräs, J. (2017). Semi-automated International Cartilage Repair Society scoring of equine articular cartilage lesions in optical coherence tomography images. Equine Veterinary Journal, 49 (4), 552-558. doi: 10.1111/evj.12637
Sarin, J. K., Brommer, H., Argüelles, D., Puhakka, P. H., Inkinen, S. I., Afara, I. O., Saarakkala, S. and Töyräs, J. (2017). Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo. Osteoarthritis and Cartilage, 25 (5), 790-798. doi: 10.1016/j.joca.2016.12.007
Rohrbach, Daniel, Inkinen, Satu I., Zatloukalová, Jana, Kadow-Romacker, Anke, Joukainen, Antti, Malo, Markus K., Mamou, Jonathan, Töyräs, Juha and Raum, Kay (2017). Regular chondrocyte spacing is a potential cause for coherent ultrasound backscatter in human articular cartilage. Journal of the Acoustical Society of America, 141 (5), 3105-3116. doi: 10.1121/1.4979339
Leppänen, Timo, Kulkas, Antti, Duce, Brett, Mervaala, Esa and Töyräs, Juha (2017). Severity of individual obstruction events is gender dependent in sleep apnea. Sleep and Breathing, 21 (2), 397-404. doi: 10.1007/s11325-016-1430-0
Duce, Brett, Kulkas, Antti, Langton, Christian, Töyräs, Juha and Hukins, Craig (2017). Amsterdam positional OSA classification: the AASM 2012 recommended hypopnoea criteria increases the number of positional therapy candidates. Sleep and Breathing, 21 (2), 411-417. doi: 10.1007/s11325-016-1432-y
Kokkonen, H. T., Chin, H. C., Töyräs, J., Jurvelin, J. S. and Quinn, T. M. (2017). Solute transport of negatively charged contrast agents across articular surface of injured cartilage. Annals of Biomedical Engineering, 45 (4), 973-981. doi: 10.1007/s10439-016-1756-6
Rieppo, Lassi, Töyräs, Juha and Saarakkala, Simo (2017). Vibrational spectroscopy of articular cartilage. Applied Spectroscopy Reviews, 52 (3), 249-266. doi: 10.1080/05704928.2016.1226182
Rieppo, Lassi, Kokkonen, Harri T., Kulmala, Katariina A.M., Kovanen, Vuokko, Lammi, Mikko J., Töyräs, Juha and Saarakkala, Simo (2017). Infrared microspectroscopic determination of collagen cross-links in articular cartilage. Journal of Biomedical Optics, 22 (3) 035007, 035007. doi: 10.1117/1.JBO.22.3.035007
Myller, Katariina A. H., Turunen, Mikael J., Honkanen, Juuso T. J., Väänänen, Sami P., Iivarinen, Jarkko T., Salo, Jari, Jurvelin, Jukka S. and Töyräs, Juha (2017). In Vivo contrast-enhanced cone beam CT provides quantitative information on articular cartilage and subchondral bone. Annals of Biomedical Engineering, 45 (3), 811-818. doi: 10.1007/s10439-016-1730-3
Danso, Elvis K., Oinas, Joonas M.T., Saarakkala, Simo, Mikkonen, Santtu, Töyräs, Juha and Korhonen, Rami K. (2017). Structure-function relationships of human meniscus. Journal of the Mechanical Behavior of Biomedical Materials, 67, 51-60. doi: 10.1016/j.jmbbm.2016.12.002
Eneh, Chibuzor T. M., Afara, Isaac O., Malo, Markus K. H., Jurvelin, Jukka S. and Töyräs, Juha (2017). Porosity predicted from ultrasound backscatter using multivariate analysis can improve accuracy of cortical bone thickness assessment. Journal of the Acoustical Society of America, 141 (1), 575-585. doi: 10.1121/1.4973572
Myllymaa, Sami, Muraja-Murro, Anu, Westeren-Punnonen, Susanna, Hukkanen, Taina, Lappalainen, Reijo, Mervaala, Esa, Töyräs, Juha, Sipilä, Kirsi and Myllymaa, Katja (2016). Assessment of the suitability of using a forehead EEG electrode set and chin EMG electrodes for sleep staging in polysomnography. Journal of Sleep Research, 25 (6), 636-645. doi: 10.1111/jsr.12425
Venäläinen, Mikko S., Mononen, Mika E., Salo, Jari, Räsänen, Lasse P., Jurvelin, Jukka S., Töyräs, Juha, Virén, Tuomas and Korhonen, Rami K. (2016). Quantitative evaluation of the mechanical risks caused by focal cartilage defects in the knee. Scientific Reports, 6 (1) 37538, 1-12. doi: 10.1038/srep37538
Sarin, Jaakko K., Amissah, Michael, Brommer, Harold, Argüelles, David, Töyräs, Juha and Afara, Isaac O. (2016). Near infrared spectroscopic mapping of functional properties of equine articular cartilage. Annals of Biomedical Engineering, 44 (11), 3335-3345. doi: 10.1007/s10439-016-1659-6
Honkanen, Juuso T. J., Turunen, Mikael J., Freedman, Jonathan D., Saarakkala, Simo, Grinstaff, Mark W., Ylärinne, Janne H., Jurvelin, Jukka S. and Töyräs, Juha (2016). Cationic contrast agent diffusion differs between cartilage and meniscus. Annals of Biomedical Engineering, 44 (10), 2913-2921. doi: 10.1007/s10439-016-1629-z
Duce, Brett, Kulkas, Antti, Langton, Christian, Töyräs, Juha and Hukins, Craig (2016). The AASM 2012 recommended hypopnea criteria increase the incidence of obstructive sleep apnea but not the proportion of positional obstructive sleep apnea. Sleep Medicine, 26, 23-29. doi: 10.1016/j.sleep.2016.07.013
Halonen, K. S., Mononen, M. E., Töyräs, J., Kröger, H., Joukainen, A. and Korhonen, R. K. (2016). Optimal graft stiffness and pre-strain restore normal joint motion and cartilage responses in ACL reconstructed knee. Journal of Biomechanics, 49 (13), 2566-2576. doi: 10.1016/j.jbiomech.2016.05.002
Ojanen, Xiaowei, Töyräs, Juha, Inkinen, Satu I., Malo, Markus K. H., Isaksson, Hanna and Jurvelin, Jukka S. (2016). Differences in acoustic impedance of fresh and embedded human trabecular bone samples - scanning acoustic microscopy and numerical evaluation. Journal of the Acoustical Society of America, 140 (3), 1931-1936. doi: 10.1121/1.4962347
Rautiainen, J., Nieminen, M. T., Salo, E. N., Kokkonen, H. T., Mangia, S., Michaeli, S., Gröhn, O., Jurvelin, J. S., Töyräs, J. and Nissi, M. J. (2016). Effect of collagen cross-linking on quantitative MRI parameters of articular cartilage. Osteoarthritis and Cartilage, 24 (9), 1656-1664. doi: 10.1016/j.joca.2016.04.017
Linder, Hans, Malo, Markus K. H., Liukkonen, Jukka, Jurvelin, Jukka S. and Töyräs, Juha (2016). Phased-array ultrasound technology enhances accuracy of dual frequency ultrasound measurements – towards improved ultrasound bone diagnostics. Journal of Medical Engineering and Technology, 40 (6), 293-297. doi: 10.1080/03091902.2016.1185472
Puhakka, Pia H, te Moller, Nikae C R, Tanska, Petri, Saarakkala, Simo, Tiitu, Virpi, Korhonen, Rami K, Brommer, Harold, Virén, Tuomas, Jurvelin, Jukka S and Töyräs, Juha (2016). Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound. Acta Orthopaedica, 87 (4), 418-424. doi: 10.1080/17453674.2016.1180578
Inkinen, Satu I., Liukkonen, Jukka, Malo, Markus K. H., Virén, Tuomas, Jurvelin, Jukka S. and Töyräs, Juha (2016). Finite difference time domain model of ultrasound propagation in agarose scaffold containing collagen or chondrocytes. Journal of the Acoustical Society of America, 140 (1), 1-7. doi: 10.1121/1.4953021
Halonen, K. S., Mononen, M. E., Jurvelin, J. S., Töyräs, J., Kłodowski, A., Kulmala, J. P. and Korhonen, R. K. (2016). Importance of patella, quadriceps forces, and depthwise cartilage structure on knee joint motion and cartilage response during gait. Journal of Biomechanical Engineering, 138 (7) 071002. doi: 10.1115/1.4033516
Puhakka, Jani, Afara, Isaac O., Paatela, Teemu, Sormaala, Markus J., Timonen, Matti A., Virén, Tuomas, Jurvelin, Jukka S., Töyräs, Juha and Kiviranta, Ilkka (2016). In vivo evaluation of the potential of high-frequency ultrasound for arthroscopic examination of the shoulder joint. Cartilage, 7 (3), 248-255. doi: 10.1177/1947603515617280
Honkanen, J. T.J., Turunen, M. J., Tiitu, V., Jurvelin, J. S. and Töyräs, J. (2016). Transport of iodine is different in cartilage and meniscus. Annals of Biomedical Engineering, 44 (7), 2114-2122. doi: 10.1007/s10439-015-1513-2
Männicke, Nils, Schöne, Martin, Liukkonen, Jukka, Fachet, Dominik, Inkinen, Satu, Malo, Markus K., Oelze, Michael L., Töyräs, Juha, Jurvelin, Jukka S. and Raum, Kay (2016). Species-independent modeling of high-frequency ultrasound backscatter in hyaline cartilage. Ultrasound in Medicine and Biology, 42 (6), 1375-1384. doi: 10.1016/j.ultrasmedbio.2016.01.018
Venäläinen, M. S., Mononen, M. E., Väänänen, S. P., Jurvelin, J. S., Töyräs, J., Virén, T. and Korhonen, R. K. (2016). Effect of bone inhomogeneity on tibiofemoral contact mechanics during physiological loading. Journal of Biomechanics, 49 (7), 1111-1120. doi: 10.1016/j.jbiomech.2016.02.033
Muhonen, Virpi, Salonius, Eve, Haaparanta, Anne-Marie, Järvinen, Elina, Paatela, Teemu, Meller, Anna, Hannula, Markus, Björkman, Mimmi, Pyhältö, Tuomo, Ellä, Ville, Vasara, Anna, Töyräs, Juha, Kellomäki, Minna and Kiviranta, Ilkka (2016). Articular cartilage repair with recombinant human type II collagen/polylactide scaffold in a preliminary porcine study. Journal of Orthopaedic Research, 34 (5), 745-753. doi: 10.1002/jor.23099
Hirvasniemi, Jukka, Thevenot, Jérôme, Kokkonen, Harri T., Finnilä, Mikko A., Venäläinen, Mikko S., Jämsä, Timo, Korhonen, Rami K., Töyräs, Juha and Saarakkala, Simo (2016). Correlation of subchondral bone density and structure from plain radiographs with micro computed tomography ex vivo. Annals of Biomedical Engineering, 44 (5), 1698-1709. doi: 10.1007/s10439-015-1452-y
Eneh, C. T.M., Malo, M. K.H., Karjalainen, J. P., Liukkonen, J., Töyräs, J. and Jurvelin, J. S. (2016). Effect of porosity, tissue density, and mechanical properties on radial sound speed in human cortical bone. Medical Physics, 43 (5), 2030-2039. doi: 10.1118/1.4942808
Leppänen, Timo, Särkkä, Mikko, Kulkas, Antti, Muraja-Murro, Anu, Kupari, Salla, Anttonen, Meri, Tiihonen, Pekka, Mervaala, Esa and Töyräs, Juha (2016). RemLogic plug-in enables clinical application of apnea-hypopnea index adjusted for severity of individual obstruction events. Journal of Medical Engineering and Technology, 40 (3), 119-126. doi: 10.3109/03091902.2016.1148791
Leppänen, Timo, Töyräs, Juha, Muraja-Murro, Anu, Kupari, Salla, Tiihonen, Pekka, Mervaala, Esa and Kulkas, Antti (2016). Length of individual apnea events is increased by supine position and modulated by severity of obstructive sleep apnea. Sleep Disorders, 2016, 9645347-13. doi: 10.1155/2016/9645347
Myllymaa, Katja, Myllymaa, Sami, Leppänen, Timo, Kulkas, Antti, Kupari, Salla, Tiihonen, Pekka, Mervaala, Esa, Seppä, Juha, Tuomilehto, Henri and Töyräs, Juha (2016). Effect of oxygen desaturation threshold on determination of OSA severity during weight loss. Sleep and Breathing, 20 (1), 33-42. doi: 10.1007/s11325-015-1180-4
Karjalainen, J. P., Riekkinen, O., Töyräs, J., Jurvelin, J. S. and Kröger, H. (2016). New method for point-of-care osteoporosis screening and diagnostics. Osteoporosis International, 27 (3), 971-977. doi: 10.1007/s00198-015-3387-4
Lasanen, R., Julkunen, P., Airaksinen, O. and Töyräs, J. (2016). Menthol concentration in topical cold gel does not have significant effect on skin cooling. Skin Research and Technology, 22 (1), 40-45. doi: 10.1111/srt.12226
Ala-Myllymäki, Juho, Honkanen, Juuso T.J., Töyräs, Juha and Afara, Isaac O. (2016). Optical spectroscopic determination of human meniscus composition. Journal of Orthopaedic Research, 34 (2), 270-278. doi: 10.1002/jor.23025
Huttunen, J. M.J., Turunen, M. J., Honkanen, J. T.J., Töyräs, J. and Jurvelin, J. S. (2016). Estimation of systematic and spatially correlated components of random signals from repeated measurements: application to contrast enhanced computer tomography measurements. SIAM Journal on Scientific Computing, 38 (1), B77-B99. doi: 10.1137/15M1017727
Puhakka, P. H., te Moller, N. C.R., Afara, I. O., Mäkelä, J. T.A., Tiitu, V., Korhonen, R. K., Brommer, H., Virén, T., Jurvelin, J. S. and Töyräs, J. (2015). Estimation of articular cartilage properties using multivariate analysis of optical coherence tomography signal. Osteoarthritis and Cartilage, 23 (12), 2206-2213. doi: 10.1016/j.joca.2015.05.034
Lepola, Pasi, Myllymaa, Sami, Töyräs, Juha, Hukkanen, Taina, Mervaala, Esa, Määttä, Sara, Lappalainen, Reijo and Myllymaa, Katja (2015). A Handy EEG Electrode Set for patients suffering from altered mental state. Journal of Clinical Monitoring and Computing, 29 (6), 697-705. doi: 10.1007/s10877-014-9652-9
Eneh, Chibuzor T. M., Liukkonen, Jukka, Malo, Markus K. H., Jurvelin, Jukka S. and Töyräs, Juha (2015). Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speed. Journal of the Acoustical Society of America, 138 (6), 3491-3499. doi: 10.1121/1.4934276
Kulkas, A., Leppänen, T., Sahlman, J., Tiihonen, P., Mervaala, E., Kokkarinen, J., Randell, J., Seppä, J., Töyräs, J. and Tuomilehto, H. (2015). Amount of weight loss or gain influences the severity of respiratory events in sleep apnea. Medical and Biological Engineering and Computing, 53 (10), 975-988. doi: 10.1007/s11517-015-1290-y
Penttilä, Pekko, Liukkonen, Jukka, Joukainen, Antti, Virén, Tuomas, Jurvelin, Jukka S., Töyräs, Juha and Kröger, Heikki (2015). Diagnosis of knee osteochondral lesions with ultrasound imaging. Arthroscopy Techniques, 4 (5), e429-e433. doi: 10.1016/j.eats.2015.04.002
Turunen, Mikael J., Töyras, Juha, Kokkonen, Harri T and Jurvelin, Jukka S. (2015). Quantitative evaluation of knee subchondral bone mineral density using cone beam computed tomography. IEEE Transactions on Medical Imaging, 34 (10) 7097073, 2186-2190. doi: 10.1109/TMI.2015.2426684
Myllymaa, Sami, Myllymaa, Katja, Kupari, Salla, Kulkas, Antti, Leppänen, Timo, Tiihonen, Pekka, Mervaala, Esa, Seppä, Juha, Tuomilehto, Henri and Töyräs, Juha (2015). Effect of different oxygen desaturation threshold levels on hypopnea scoring and classification of severity of sleep apnea. Sleep and Breathing, 19 (3), 947-954. doi: 10.1007/s11325-015-1118-x
Afara, Isaac O., Hauta-Kasari, Markku, Jurvelin, Jukka S., Oloyede, Adekunle and Töyräs, Juha (2015). Optical absorption spectra of human articular cartilage correlate with biomechanical properties, histological score and biochemical composition. Physiological Measurement, 36 (9) 1913, 1913-1928. doi: 10.1088/0967-3334/36/9/1913
Honkanen, J. T J, Danso, E. K., Suomalainen, J. S., Tiitu, V., Korhonen, R. K., Jurvelin, J. S. and Töyräs, J. (2015). Contrast enhanced imaging of human meniscus using cone beam CT. Osteoarthritis and Cartilage, 23 (8), 1367-1376. doi: 10.1016/j.joca.2015.03.037
Muraja-Murro, Anu, Mervaala, Esa, Westeren-Punnonen, Susanna, Lepola, Pasi, Töyräs, Juha, Myllymaa, Sami, Julkunen, Petro, Kantanen, Anne-Mari, Kälviäinen, Reetta and Myllymaa, Katja (2015). Forehead EEG electrode set versus full-head scalp EEG in 100 patients with altered mental state. Epilepsy and Behavior, 49, 245-249. doi: 10.1016/j.yebeh.2015.04.041
Inkinen, Satu I., Liukkonen, Jukka, Tiitu, Virpi, Virén, Tuomas, Jurvelin, Jukka S. and Töyräs, Juha (2015). Ultrasound backscattering is anisotropic in bovine articular cartilage. Ultrasound in Medicine and Biology, 41 (7), 1958-1966. doi: 10.1016/j.ultrasmedbio.2015.03.021
Danso, E. K., Mäkelä, J. T.A., Tanska, P., Mononen, M. E., Honkanen, J. T.J., Jurvelin, J. S., Töyräs, J., Julkunen, P. and Korhonen, R. K. (2015). Characterization of site-specific biomechanical properties of human meniscus -importance of collagen and fluid on mechanical nonlinearities. Journal of Biomechanics, 48 (8), 1499-1507. doi: 10.1016/j.jbiomech.2015.01.048
Lasanen, R, Piippo-Savolainen, E, Remes-Pakarinen, T, Kröger, L, Heikkilä, A, Julkunen, P, Karhu, J and Töyräs, J (2015). Thermal imaging in screening of joint inflammation and rheumatoid arthritis in children. Physiological measurement, 36 (2), 273-82. doi: 10.1088/0967-3334/36/2/273
Ojanen, X., Isaksson, H., Töyräs, J., Turunen, M. J., Malo, M. K H, Halvari, A. and Jurvelin, J. S. (2015). Relationships between tissue composition and viscoelastic properties in human trabecular bone. Journal of Biomechanics, 48 (2), 269-275. doi: 10.1016/j.jbiomech.2014.11.034
Venäläinen, Mikko S., Mononen, Mika E., Jurvelin, Jukka S., Töyräs, Juha, Virén, Tuomas and Korhonen, Rami K. (2014). Importance of material properties and porosity of bone on mechanical response of articular cartilage in human knee joint - a two-dimensional finite element study. Journal of Biomechanical Engineering, 136 (12) 121005. doi: 10.1115/1.4028801
Puhakka, P. H., Ylärinne, J. H., Lammi, M. J., Saarakkala, S., Tiitu, V., Kröger, H., Virén, T., Jurvelin, J. S. and Töyräs, J. (2014). Dependence of light attenuation and backscattering on collagen concentration and chondrocyte density in agarose scaffolds. Physics in Medicine and Biology, 59 (21), 6537-6548. doi: 10.1088/0031-9155/59/21/6537
Kulkas, Antti, Muraja-Murro, Anu, Tiihonen, Pekka, Mervaala, Esa and Töyräs, Juha (2014). Morbidity and mortality risk ratios are elevated in severe supine dominant OSA: a long-term follow-up study. Sleep and Breathing, 19 (2), 653-660. doi: 10.1007/s11325-014-1071-0
Kulkas, A., Leppänen, T., Sahlman, J., Tiihonen, P., Mervaala, E., Kokkarinen, J., Randell, J., Seppä, J., Töyräs, J. and Tuomilehto, H. (2014). Weight loss alters severity of individual nocturnal respiratory events depending on sleeping position. Physiological Measurement, 35 (10) 2037, 2037-2052. doi: 10.1088/0967-3334/35/10/2037
Muraja-Murro, A., Kulkas, A., Hiltunen, M., Kupari, S., Hukkanen, T., Tiihonen, P., Mervaala, E. and Töyräs, J. (2014). Adjustment of apnea-hypopnea index with severity of obstruction events enhances detection of sleep apnea patients with the highest risk of severe health consequences. Sleep and Breathing, 18 (3), 641-647. doi: 10.1007/s11325-013-0927-z
Inkinen, S., Liukkonen, J., Ylärinne, J. H., Puhakka, P. H., Lammi, M. J., Virén, T., Jurvelin, J. S. and Töyräs, J. (2014). Collagen and chondrocyte concentrations control ultrasound scattering in aAgarose scaffolds. Ultrasound in Medicine and Biology, 40 (9), 2162-2171. doi: 10.1016/j.ultrasmedbio.2014.03.016
Liukkonen, Jukka, Lehenkari, Petri, Hirvasniemi, Jukka, Joukainen, Antti, Virén, Tuomas, Saarakkala, Simo, Nieminen, Miika T., Jurvelin, Jukka S. and Töyräs, Juha (2014). Ultrasound arthroscopy of human knee cartilage and subchondral bone in vivo. Ultrasound in Medicine and Biology, 40 (9), 2039-2047. doi: 10.1016/j.ultrasmedbio.2014.04.001
Lepola, Pasi, Myllymaa, Sami, Töyräs, Juha, Mervaala, Esa, Lappalainen, Reijo and Myllymaa, Katja (2014). Shielded design of screen-printed EEG electrode set reduces interference pick-up. IEEE Sensors Journal, 14 (8) 6780623, 2692-2697. doi: 10.1109/JSEN.2014.2314318
Halonen, K. S., Mononen, M. E., Jurvelin, J. S., Töyräs, J., Salo, J. and Korhonen, R. K. (2014). Deformation of articular cartilage during static loading of a knee joint - experimental and finite element analysis. Journal of Biomechanics, 47 (10), 2467-2474. doi: 10.1016/j.jbiomech.2014.04.013
Lepola, Pasi, Myllymaa, Sami, Töyräs, Juha, Muraja-Murro, Anu, Mervaala, Esa, Lappalainen, Reijo and Myllymaa, Katja (2014). Screen-printed EEG electrode set for emergency use. Sensors and Actuators, A: Physical, 213, 19-26. doi: 10.1016/j.sna.2014.03.029
Malo, M. K.H., Töyräs, J., Karjalainen, J. P., Isaksson, H., Riekkinen, O. and Jurvelin, J. S. (2014). Ultrasound backscatter measurements of intact human proximal femurs - relationships of ultrasound parameters with tissue structure and mineral density. Bone, 64, 240-245. doi: 10.1016/j.bone.2014.04.014
Huttunen, J. M. J., Kokkonen, H. T., Jurvelin, J. S., Töyräs, J. and Kaipio, J. P. (2014). Estimation of fixed charge density and diffusivity profiles in cartilage using contrast enhanced computer tomography. International Journal for Numerical Methods in Engineering, 98 (5), 371-390. doi: 10.1002/nme.4634
Husso, M., Sipola, P., Kuittinen, T., Manninen, H., Vainio, P., Hartikainen, J., Saarakkala, S., Töyräs, J. and Kuikka, J. (2014). Assessment of myocardial perfusion with MRI using a modified dual bolus method. Physiological Measurement, 35 (4), 533-547. doi: 10.1088/0967-3334/35/4/533
Kokkonen, Harri T., Suomalainen, Juha-Sampo, Joukainen, Antti, Kröger, Heikki, Sirola, Joonas, Jurvelin, Jukka S., Salo, Jari and Töyräs, Juha (2014). In vivo diagnostics of human knee cartilage lesions using delayed CBCT arthrography. Journal of Orthopaedic Research, 32 (3), 403-412. doi: 10.1002/jor.22521
Niemelä, Tytti, Virén, Tuomas, Liukkonen, Jukka, Argüelles, David, te Moller, Nikae C R, Puhakka, Pia H, Jurvelin, Jukka S, Tulamo, Riitta-Mari and Töyräs, Juha (2014). Application of optical coherence tomography enhances reproducibility of arthroscopic evaluation of equine joints. Acta veterinaria Scandinavica, 56 ARTN 3. doi: 10.1186/1751-0147-56-3
Qu, Chengjuan, Hirviniemi, Mikko, Tiitu, Virpi, Jurvelin, Jukka S., Töyräs, Juha and Lammi, Mikko J. (2014). Effects of freeze-thaw cycle with and without proteolysis inhibitors and cryopreservant on the biochemical and biomechanical properties of articular cartilage. Cartilage, 5 (2), 97-106. doi: 10.1177/1947603513515998
Muraja-Murro, Anu, Kulkas, Antti, Hiltunen, Mikko, Kupari, Salla, Hukkanen, Taina, Tiihonen, Pekka, Mervaala, Esa and Töyräs, Juha (2013). The severity of individual obstruction events is related to increased mortality rate in severe obstructive sleep apnea. Journal of Sleep Research, 22 (6), 663-669. doi: 10.1111/jsr.12070
Kulmala, K. A M, Karjalainen, H. M., Kokkonen, H. T., Tiitu, V., Kovanen, V., Lammi, M. J., Jurvelin, J. S., Korhonen, R. K. and Töyräs, J. (2013). Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking - contribution of steric and electrostatic effects. Medical Engineering and Physics, 35 (10), 1415-1420. doi: 10.1016/j.medengphy.2013.03.010
Te Moller, N. C.R., Brommer, H., Liukkonen, J., Virén, T., Timonen, M., Puhakka, P. H., Jurvelin, J. S., Van Weeren, P. R. and Töyräs, J. (2013). Arthroscopic optical coherence tomography provides detailed information on articular cartilage lesions in horses. The Veterinary Journal, 197 (3), 589-595. doi: 10.1016/j.tvjl.2013.05.031
Muraja-Murro, A., Eskola, K., Kolari, T., Tiihonen, P., Hukkanen, T., Tuomilehto, H., Peltonen, M., Mervaala, E. and Töyräs, J. (2013). Mortality in middle-aged men with obstructive sleep apnea in Finland. Sleep and Breathing, 17 (3), 1047-1053. doi: 10.1007/s11325-012-0798-8
Kulkas, A., Leppänen, T., Sahlman, J., Tiihonen, P., Mervaala, E., Kokkarinen, J., Randell, J., Seppä, J., Tuomilehto, H. and Töyräs, J. (2013). Novel parameters reflect changes in morphology of respiratory events during weight loss. Physiological Measurement, 34 (9), 1013-1026. doi: 10.1088/0967-3334/34/9/1013
Liukkonen, J., Hirvasniemi, J., Joukainen, A., Penttilä, P., Virén, T., Saarakkala, S., Kröger, H., Jurvelin, J. S. and Töyräs, J. (2013). Arthroscopic ultrasound technique for simultaneous quantitative assessment of articular cartilage and subchondral bone: an in vitro and in vivo feasibility study. Ultrasound in Medicine and Biology, 39 (8), 1460-1468. doi: 10.1016/j.ultrasmedbio.2013.03.026
Kulkas, Antti, Tiihonen, Pekka, Julkunen, Petro, Mervaala, Esa and Töyräs, Juha (2013). Novel parameters indicate significant differences in severity of obstructive sleep apnea with patients having similar apnea-hypopnea index. Medical and Biological Engineering and Computing, 51 (6), 697-708. doi: 10.1007/s11517-013-1039-4
Myllymaa, Sami, Lepola, Pasi, Töyräs, Juha, Hukkanen, Taina, Mervaala, Esa, Lappalainen, Reijo and Myllymaa, Katja (2013). New disposable forehead electrode set with excellent signal quality and imaging compatibility. Journal of Neuroscience Methods, 215 (1), 103-109. doi: 10.1016/j.jneumeth.2013.02.003
Halonen, K. S., Mononen, M. E., Jurvelin, J. S., Töyräs, J. and Korhonen, R. K. (2013). Importance of depth-wise distribution of collagen and proteoglycans in articular cartilage - a 3D finite element study of stresses and strains in human knee joint. Journal of Biomechanics, 46 (6), 1184-1192. doi: 10.1016/j.jbiomech.2012.12.025
Malo, M. K. H., Rohrbach, D., Isaksson, H., Töyräs, J., Jurvelin, J. S., Tamminen, I. S., Kröger, H. and Raum, K. (2013). Longitudinal elastic properties and porosity of cortical bone tissue vary with age in human proximal femur. Bone, 53 (2), 451-458. doi: 10.1016/j.bone.2013.01.015
Hirvasniemi, J., Kulmala, K. A M, Lammentausta, E., Ojala, R., Lehenkari, P., Kamel, A., Jurvelin, J. S., Töyräs, J., Nieminen, M. T. and Saarakkala, S. (2013). In vivo comparison of delayed gadolinium-enhanced MRI of cartilage and delayed quantitative CT arthrography in imaging of articular cartilage. Osteoarthritis and Cartilage, 21 (3), 434-442. doi: 10.1016/j.joca.2012.12.009
Pulkkinen, H. J., Tiitu, V., Valonen, P., Jurvelin, J. S., Rieppo, L., Töyräs, J., Silvast, T. S., Lammi, M. J. and Kiviranta, I. (2013). Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in rabbit. Osteoarthritis and Cartilage, 21 (3), 481-490. doi: 10.1016/j.joca.2012.12.004
Kulkas, A., Tiihonen, P., Eskola, K., Julkunen, P., Mervaala, E. and Töyräs, J. (2013). Novel parameters for evaluating severity of sleep disordered breathing and for supporting diagnosis of sleep apnea-hypopnea syndrome. Journal of Medical Engineering and Technology, 37 (2), 135-143. doi: 10.3109/03091902.2012.754509
Silvast, Tuomo S., Jurvelin, Jukka S., Tiitu, Virpi, Quinn, Thomas M. and Töyräs, Juha (2013). Bath concentration of anionic contrast agents does not affect their diffusion and distribution in articular cartilage in vitro. Cartilage, 4 (1), 42-51. doi: 10.1177/1947603512451023
Muraja-Murro, A., Nurkkala, J., Tiihonen, P., Hukkanen, T., Tuomilehto, H., Kokkarinen, J., Mervaala, E. and Töyräs, J. (2012). Total duration of apnea and hypopnea events and average desaturation show significant variation in patients with a similar apneahypopnea index. Journal of Medical Engineering and Technology, 36 (8), 393-398. doi: 10.3109/03091902.2012.712201
Kokkonen, Harri T., Aula, Antti S., Kröger, Heikki, Suomalainen, Juha-Sampo, Lammentausta, Eveliina, Mervaala, Esa, Jurvelin, Jukka S. and Töyräs, Juha (2012). Delayed computed tomography arthrography of human knee cartilage in vivo. Cartilage, 3 (4), 334-341. doi: 10.1177/1947603512447300
Kinnunen, Jussi, Kokkonen, Harri T., Kovanen, Vuokko, Hauta-Kasari, Markku, Vahimaa, Pasi, Lammi, Mikko J., Töyräs, Juha and Jurvelin, Jukka S. (2012). Nondestructive fluorescence-based quantification of threose-induced collagen cross-linking in bovine articular cartilage. Journal of Biomedical Optics, 17 (9) 097003. doi: 10.1117/1.JBO.17.9.097003
Kulmala, Katariina A.M., Pulkkinen, H. J., Rieppo, L., Tiitu, V., Kiviranta, I., Brünott, A., Brommer, H., van Weeren, R., Brama, P. A.J., Mikkola, M. T., Korhonen, R. K., Jurvelin, J. S. and Töyräs, J. (2012). Contrast-Enhanced Micro-Computed Tomography in Evaluation of Spontaneous Repair of Equine Cartilage. Cartilage, 3 (3), 235-244. doi: 10.1177/1947603511424173
Virén, T., Timonen, M., Tyrväinen, H., Tiitu, V., Jurvelin, J. S. and Töyräs, J. (2012). Ultrasonic evaluation of acute impact injury of articular cartilage in vitro. Osteoarthritis and Cartilage, 20 (7), 719-726. doi: 10.1016/j.joca.2012.03.018
Karjalainen, J. P., Riekkinen, O., Töyräs, J., Hakulinen, M., Kröger, H., Rikkonen, T., Salovaara, K. and Jurvelin, J. S. (2012). Multi-site bone ultrasound measurements in elderly women with and without previous hip fractures. Osteoporosis International, 23 (4), 1287-1295. doi: 10.1007/s00198-011-1682-2
Virén, T., Huang, Y. P., Saarakkala, S., Pulkkinen, H., Tiitu, V., Linjama, A., Kiviranta, I., Lammi, M. J., Brnott, A., Brommer, H., Van Weeren, R., Brama, P. A.J., Zheng, Y. P., Jurvelin, J. S. and Töyrs, J. (2012). Comparison of ultrasound and optical coherence tomography techniques for evaluation of integrity of spontaneously repaired horse cartilage. Journal of Medical Engineering and Technology, 36 (3), 185-192. doi: 10.3109/03091902.2012.663054
Turunen, M. J., Töyräs, J., Lammi, M. J., Jurvelin, J. S. and Korhonen, R. K. (2012). Hyperosmolaric contrast agents in cartilage tomography may expose cartilage to overload-induced cell death. Journal of Biomechanics, 45 (3), 497-503. doi: 10.1016/j.jbiomech.2011.11.049
Salo, E. N., Nissi, M. J., Kulmala, K. A M, Tiitu, V., Töyräs, J. and Nieminen, M. T. (2012). Diffusion of Gd-DTPA2- into articular cartilage. Osteoarthritis and Cartilage, 20 (2), 117-126. doi: 10.1016/j.joca.2011.11.016
Lötjönen, Pauno, Julkunen, Petro, Tiitu, Virpi, Jurvelin, Jukka S. and Töyräs, Juha (2011). Ultrasound speed varies in articular cartilage under indentation loading. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 58 (12) 6141171, 2772-2780. doi: 10.1109/TUFFC.2011.2143
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Kokkonen, H. T., Jurvelin, J. S., Tiitu, V. and Töyräs, J. (2011). Detection of mechanical injury of articular cartilage using contrast enhanced computed tomography. Osteoarthritis and Cartilage, 19 (3), 295-301. doi: 10.1016/j.joca.2010.12.012
Huang, Yan-Ping, Saarakkala, Simo, Toyras, Juha, Wang, Li-Ke, Jurvelin, Jukka S. and Zheng, Yong-Ping (2011). Effects of optical beam angle on quantitative optical coherence tomography (OCT) in normal and surface degenerated bovine articular cartilage. Physics in Medicine and Biology, 56 (2), 491-509. doi: 10.1088/0031-9155/56/2/013
Isaksson, H., Töyräs, J., Hakulinen, M., Aula, A. S., Tamminen, I., Julkunen, P., Kröger, H. and Jurvelin, J. S. (2011). Structural parameters of normal and osteoporotic human trabecular bone are affected differently by microCT image resolution. Osteoporosis International, 22 (1), 167-177. doi: 10.1007/s00198-010-1219-0
Virén, Tuomas, Saarakkala, Simo, Tiitu, Virpi, Puhakka, Jani, Kiviranta, Ilkka, Jurvelin, Jukka S. and Töyräs, Juha (2011). Ultrasound evaluation of mechanical injury of bovine knee articular cartilage under arthroscopic control. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 58 (1) 5688408, 148-155. doi: 10.1109/TUFFC.2011.1781
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Timonen, M. A., TÖyräs, J., Aula, A. S., Karjalainen, J. P., Riekkinen, O. and Jurvelin, J. S. (2010). Technical and practical improvements in arthroscopic indentation technique for diagnostics of articular cartilage softening. Journal of Medical Engineering and Technology, 35 (1), 40-46. doi: 10.3109/03091902.2010.525684
Kulmala, K. A.M., Korhonen, R. K., Julkunen, P., Jurvelin, J. S., Quinn, T. M., Kröger, H. and Töyräs, J. (2010). Diffusion coefficients of articular cartilage for different CT and MRI contrast agents. Medical Engineering and Physics, 32 (8), 878-882. doi: 10.1016/j.medengphy.2010.06.002
Virén, Tuomas, Saarakkala, Simo, Jurvelin, Jukka S., Pulkkinen, Hertta J., Tiitu, Virpi, Valonen, Piia, Kiviranta, Ilkka, Lammi, Mikko J. and Töyräs, Juha (2010). Quantitative evaluation of spontaneously and surgically repaired rabbit articular cartilage using intra-articular ultrasound method in situ. Ultrasound in Medicine and Biology, 36 (5), 833-839. doi: 10.1016/j.ultrasmedbio.2010.02.015
Kaleva, Erna, Liukkonen, Jukka, Töyräs, Juha, Saarakkala, Simo, Kiviranta, Panu and Jurvelin, Jukka (2010). 2-D finite difference time domain model of ultrasound reflection from normal and osteoarthritic human articular cartilage surface. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 57 (4) 5442883, 892-899. doi: 10.1109/TUFFC.2010.1493
Malo, Markus K.H., Karjalainen, Janne P., Isaksson, Hanna, Riekkinen, Ossi, Jurvelin, Jukka S. and Töyräs, Juha (2010). Numerical Analysis of Uncertainties in Dual Frequency Bone Ultrasound Technique. Ultrasound in Medicine and Biology, 36 (2), 288-294. doi: 10.1016/j.ultrasmedbio.2009.10.008
Silvast, Tuomo S., Kokkonen, Harri T., Jurvelin, Jukka S., Quinn, Thomas M., Nieminen, Miika T. and Töyräs, Juha (2009). Diffusion and near-equilibrium distribution of MRI and CT contrast agents in articular cartilage. Physics in Medicine and Biology, 54 (22), 6823-6836. doi: 10.1088/0031-9155/54/22/005
Aula, A. S., Jurvelin, J. S. and Töyräs, J. (2009). Simultaneous computed tomography of articular cartilage and subchondral bone. Osteoarthritis and Cartilage, 17 (12), 1583-1588. doi: 10.1016/j.joca.2009.06.010
Virén, T., Saarakkala, S., Kaleva, E., Nieminen, H. J., Jurvelin, J. S. and Töyräs, J. (2009). Minimally Invasive Ultrasound Method for Intra-Articular Diagnostics of Cartilage Degeneration. Ultrasound in Medicine and Biology, 35 (9), 1546-1554. doi: 10.1016/j.ultrasmedbio.2009.04.004
Kiviranta, Panu, Lammentausta, Eveliina, Töyräs, Juha, Nieminen, Heikki J., Julkunen, Petro, Kiviranta, Ilkka and Jurvelin, Jukka S. (2009). Differences in Acoustic Properties of Intact and Degenerated Human Patellar Cartilage During Compression. Ultrasound in Medicine and Biology, 35 (8), 1367-1375. doi: 10.1016/j.ultrasmedbio.2009.03.003
Kaleva, E., Saarakkala, S., Jurvelin, J. S., Virén, T. and Töyräs, J. (2009). Effects of Ultrasound Beam Angle and Surface Roughness on the Quantitative Ultrasound Parameters of Articular Cartilage. Ultrasound in Medicine and Biology, 35 (8), 1344-1351. doi: 10.1016/j.ultrasmedbio.2009.03.009
Karjalainen, Janne P., Töyräs, Juha, Riekkinen, Ossi, Hakulinen, Mikko and Jurvelin, Jukka S. (2009). Ultrasound Backscatter Imaging Provides Frequency-Dependent Information on Structure, Composition and Mechanical Properties of Human Trabecular Bone. Ultrasound in Medicine and Biology, 35 (8), 1376-1384. doi: 10.1016/j.ultrasmedbio.2009.03.011
Kaleva, Erna, Töyräs, Juha, Jurvelin, Jukka S., Virén, Tuomas and Saarakkala, Simo (2009). Effects of ultrasound frequency, temporal sampling frequency, and spatial sampling step on the quantitative ultrasound parameters of articular cartilage. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 56 (7) 5116864, 1383-1393. doi: 10.1109/TUFFC.2009.1194
Tiihonen, P., Hukkanen, T., Tuomilehto, H., Mervaala, E., Paakkonen, A. and Toyras, J. (2009). Accuracy of automatic analysis of ambulatory recordings of nocturnal breathing disorders is significantly instrumentation dependent. Journal of Medical Engineering and Technology, 33 (5), 386-393. doi: 10.1080/03091900902739999
Lötjönen, Pauno, Julkunen, Petro, Töyräs, Juha, Lammi, Mikko J., Jurvelin, Jukka S. and Nieminen, Heikki J. (2009). Strain-Dependent Modulation of Ultrasound Speed in Articular Cartilage Under Dynamic Compression. Ultrasound in Medicine and Biology, 35 (7), 1177-1184. doi: 10.1016/j.ultrasmedbio.2009.03.002
Myllymaa, Sami, Myllymaa, Katja, Korhonen, Hannu, Töyräs, Juha, Jääskeläinen, Juha E., Djupsund, Kaj, Tanila, Heikki and Lappalainen, Reijo (2009). Fabrication and testing of polyimide-based microelectrode arrays for cortical mapping of evoked potentials. Biosensors and Bioelectronics, 24 (10), 3067-3072. doi: 10.1016/j.bios.2009.03.028
Tiihonen, Pekka, Hukkanen, Taina, Tuomilehto, Henri, Mervaala, Esa and Töyräs, Juha (2009). Evaluation of a novel ambulatory device for screening of sleep apnea. Telemedicine and e-Health, 15 (3), 283-289. doi: 10.1089/tmj.2008.0118
Silvast, T. S., Jurvelin, J. S., Aula, A. S., Lammi, M. J. and Toyras, J. (2009). Contrast agent-enhanced computed tomography of articular cartilage: Association with tissue composition and properties. Acta Radiologica, 50 (1), 78-85. doi: 10.1080/02841850802572526
Aula, A. S., Töyräs, J., Hakulinen, M. A. and Jurvelin, J. S. (2009). Effect of Bone Marrow on Acoustic Properties of Trabecular Bone - 3D Finite Difference Modeling Study. Ultrasound in Medicine and Biology, 35 (2), 308-318. doi: 10.1016/j.ultrasmedbio.2008.08.002
Tiihonen, Pekka, Päkkönen, A., Mervaala, E., Hukkanen, T. and Töyräs, J. (2009). Design, construction and evaluation of an ambulatory device for screening of sleep apnea. Medical and Biological Engineering and Computing, 47 (1), 59-66. doi: 10.1007/s11517-008-0418-8
Nieminen, Heikki J., Zheng, Y. P., Saarakkala, S., Wang, Q., Töyräs, J., Huang, Y. P. and Jurvelin, J. S. (2009). Quantitative assessment of articular cartilage using high-frequency ultrasound: Research findings and diagnostic prospects. Critical Reviews in Biomedical Engineering, 37 (6), 461-494. doi: 10.1615/CritRevBiomedEng.v37.i6.20
Silvast, T. S., Jurvelin, J. S., Lammi, M. J. and Töyräs, J. (2009). pQCT study on diffusion and equilibrium distribution of iodinated anionic contrast agent in human articular cartilage - associations to matrix composition and integrity. Osteoarthritis and Cartilage, 17 (1), 26-32. doi: 10.1016/j.joca.2008.05.012
Karjalainen, J., Töyräs, J., Rikkonen, T., Jurvelin, J. S. and Riekkinen, O. (2008). Dual-frequency ultrasound technique minimizes errors induced by soft tissue in ultrasound bone densitometry. Acta Radiologica, 49 (9), 1038-1041. doi: 10.1080/02841850802325982
Riekkinen, O., Hakulinen, M. A., Töyräs, J. and Jurvelin, J. S. (2008). Dual-Frequency Ultrasound-New Pulse-Echo Technique for Bone Densitometry. Ultrasound in Medicine and Biology, 34 (10), 1703-1708. doi: 10.1016/j.ultrasmedbio.2008.03.018
Kiviranta, P., Lammentausta, E., Töyräs, J., Kiviranta, I. and Jurvelin, J. S. (2008). Indentation diagnostics of cartilage degeneration. Osteoarthritis and Cartilage, 16 (7), 796-804. doi: 10.1016/j.joca.2007.10.016
Kurkijärvi, Jatta E., Nissi, Mikko J., Rieppo, Jarno, Töyräs, Juha, Kiviranta, Ilkka, Nieminen, Miika T. and Jurvelin, Jukka S. (2008). The zonal architecture of human articular cartilage described by T2 relaxation time in the presence of Gd-DTPA2-
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Tiihonen, Pekka, Kinnunen, Jukka, Töyräs, Juha, Mervaala, Esa and Pääkkönen, Ari (2008). A portable device for intensive care brain function monitoring with event-related potentials. Computer Methods and Programs in Biomedicine, 89 (1), 83-92. doi: 10.1016/j.cmpb.2007.10.010
Kaleva, E., Saarakkala, S., Töyräs, J., Nieminen, H. J. and Jurvelin, J. S. (2008). In-Vitro Comparison of Time-Domain, Frequency-Domain and Wavelet Ultrasound Parameters in Diagnostics of Cartilage Degeneration. Ultrasound in Medicine and Biology, 34 (1), 155-159. doi: 10.1016/j.ultrasmedbio.2007.06.028
Karjalainen, Jarme, Riekkinen, Ossi, Töyräs, Juha, Kröger, Heikki and Jurvelin, Jukka (2008). Ultrasonic assessment of cortical bone thickness in vitro and in vivo. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 55 (10) 4638905, 2191-2197. doi: 10.1109/TUFFC.918
Riekkinen, O., Hakulinen, M. A., Töyräs, J. and Jurvelin, J. S. (2007). Spatial variation of acoustic properties is related with mechanical properties of trabecular bone. Physics in Medicine and Biology, 52 (23), 6961-6968. doi: 10.1088/0031-9155/52/23/013
Nieminen, Heikki J., Julkunen, Petro, Töyräs, Juha and Jurvelin, Jukka S. (2007). Ultrasound Speed in Articular Cartilage Under Mechanical Compression. Ultrasound in Medicine and Biology, 33 (11), 1755-1766. doi: 10.1016/j.ultrasmedbio.2007.06.001
Sierpowska, J., Lammi, M. J., Hakulinen, M. A., Jurvelin, J. S., Lappalainen, R. and Töyräs, J. (2007). Effect of human trabecular bone composition on its electrical properties. Medical Engineering and Physics, 29 (8), 845-852. doi: 10.1016/j.medengphy.2006.09.007
Nissi, M. J., Rieppo, J., Töyräs, J., Laasanen, M. S., Kiviranta, I., Nieminen, M. T. and Jurvelin, J. S. (2007). Estimation of mechanical properties of articular cartilage with MRI - dGEMRIC, T2 and T1 imaging in different species with variable stages of maturation. Osteoarthritis and Cartilage, 15 (10), 1141-1148. doi: 10.1016/j.joca.2007.03.018
Saarakkala, Simo, Jurvelin, Jukka S., Zheng, Yong-Ping, Nieminen, Heikki J. and Töyräs, Juha (2007). Quantitative Information From Ultrasound Evaluation of Articular Cartilage Should Be Interpreted With Care. Arthroscopy - Journal of Arthroscopic and Related Surgery, 23 (10), 1137-1138. doi: 10.1016/j.arthro.2007.08.015
Lammentausta, E., Kiviranta, P., Töyräs, J., Hyttinen, M. M., Kiviranta, I., Nieminen, M. T. and Jurvelin, J. S. (2007). Quantitative MRI of parallel changes of articular cartilage and underlying trabecular bone in degeneration. Osteoarthritis and Cartilage, 15 (10), 1149-1157. doi: 10.1016/j.joca.2007.03.019
Riekkinen, O., Hakulinen, M. A., Lammi, M. J., Jurvelin, J. S., Kallioniemi, A. and Töyräs, J. (2007). Acoustic Properties of Trabecular Bone-Relationships to Tissue Composition. Ultrasound in Medicine and Biology, 33 (9), 1438-1444. doi: 10.1016/j.ultrasmedbio.2007.04.004
Kallioniemi, A. S., Jurvelin, J. S., Nieminen, M. T., Lammi, M. J. and Töyräs, J. (2007). Contrast agent enhanced pQCT of articular cartilage. Physics in Medicine and Biology, 52 (4) 024, 1209-1219. doi: 10.1088/0031-9155/52/4/024
Kiviranta, Panu, Töyräs, J., Nieminen, M. T., Laasanen, M. S., Saarakkala, S., Nieminen, H. J., Nissi, M. J. and Jurvelin, J. S. (2007). Comparison of novel clinically applicable methodology for sensitive diagnostics of cartilage degeneration. European Cells and Materials, 13, 46-55. doi: 10.22203/eCM.v013a05
Qu, Cheng-Juan, Rieppo, Jarno, Hyttinen, Mika, Lammi, Mikko J., Kiviranta, Ilkka, Kurkijärvi, Jatta, Jurvelin, Jukka and Töyräs, Juha (2007). Human articular cartilage proteoglycans are not undersulfated in osteoarthritis. Connective Tissue Research, 48 (1), 27-33. doi: 10.1080/03008200601044128
Nissi, M. J., Rieppo, J., Töyräs, J., Laasanen, M. S., Kiviranta, I., Jurvelin, J. S. and Nieminen, M. T. (2006). T2 relaxation time mapping reveals age- and species-related diversity of collagen network architecture in articular cartilage. Osteoarthritis and Cartilage, 14 (12), 1265-1271. doi: 10.1016/j.joca.2006.06.002
Sierpowska, J., Hakulinen, M. A., Töyräs, J., Day, J. S., Weinans, H., Kiviranta, I., Jurvelin, J. S. and Lappalainen, R. (2006). Interrelationships between electrical properties and microstructure of human trabecular bone. Physics in Medicine and Biology, 51 (20) 014, 5289-5303. doi: 10.1088/0031-9155/51/20/014
Saarakkala, Simo, Laasanen, Mikko S., Jurvelin, Jukka S. and Töyräs, Juha (2006). Quantitative ultrasound imaging detects degenerative changes in articular cartilage surface and subchondral bone. Physics in Medicine and Biology, 51 (20) 017, 5333-5346. doi: 10.1088/0031-9155/51/20/017
Riekkinen, Ossi, Hakulinen, Mikko A., Timonen, Matti, Töyräs, Juha and Jurvelin, Jukka S. (2006). Influence of overlying soft tissues on trabecular bone acoustic measurement at various ultrasound frequencies. Ultrasound in Medicine and Biology, 32 (7), 1073-1083. doi: 10.1016/j.ultrasmedbio.2006.03.012
Kiviranta, Panu, Rieppo, Jarno, Korhonen, Rami K., Julkunen, Petro, Töyräs, Juha and Jurvelin, Jukka S. (2006). Collagen network primarily controls poisson's ratio of bovine articular cartilage in compression. Journal of Orthopaedic Research, 24 (4), 690-699. doi: 10.1002/jor.20107
Hakulinen, Mikko A., Day, Judd S., Töyräs, Juha, Weinans, Harrie and Jurvelin, Jukka S. (2006). Ultrasonic characterization of human trabecular bone microstructure. Physics in Medicine and Biology, 51 (6), 1633-1648. doi: 10.1088/0031-9155/51/6/019
Laasanen, M. S., Töyräs, J., Vasara, A., Saarakkala, S., Hyttinen, M. M., Kiviranta, I. and Jurvelin, Jukka S. (2006). Quantitative ultrasound imaging of spontaneous repair of porcine cartilage. Osteoarthritis and Cartilage, 14 (3), 258-263. doi: 10.1016/j.joca.2005.09.011
Laasanen, Mikko S., Saarakkala, Simo, Töyräs, Juha, Rieppo, Jarno and Jurvelin, Jukka S. (2005). Site-specific ultrasound reflection properties and superficial collagen content of bovine knee articular cartilage. Physics in Medicine and Biology, 50 (14), 3221-3233. doi: 10.1088/0031-9155/50/14/002
Hakulinen, Mikko A., Day, Judd S., Töyräs, Juha, Timonen, Matti, Kröger, Heikki, Weinans, Harrie, Kiviranta, Ilkka and Jurvelin, Jukka S. (2005). Prediction of density and mechanical properties of human trabecular bone in vitro by using ultrasound transmission and backscattering measurements at 0.2-6.7 MHz frequency range. Physics in Medicine and Biology, 50 (8), 1629-1642. doi: 10.1088/0031-9155/50/8/001
Töyräs, Juha, Korhonen, Rami K., Voutilainen, Tanja, Jurvelin, Jukka S. and Lappalainen, Reijo (2005). Improvement of arthroscopic cartilage stiffness probe using amorphous diamond coating. Journal of Biomedical Materials Research - Part B Applied Biomaterials, 73 (1), 15-22. doi: 10.1002/jbm.b.30173
Lammi, Mikko J, Qu, Cheng-Juan, Laasanen, Mikko S, Saarakkala, Simo, Rieppo, Jarno, Jurvelin, Jukka S and Töyräs, Juha (2004). Undersulfated chondroitin sulfate does not increase in osteoarthritic cartilage. The Journal of rheumatology, 31 (12), 2449-53.
Hakulinen, Mikko A., Töyräs, Juha, Saarakkala, Simo, Hirvonen, Jani, Kröger, Heikki and Jurvelin, Jukka S. (2004). Ability of ultrasound backscattering to predict mechanical properties of bovine trabecular bone. Ultrasound in Medicine and Biology, 30 (7), 919-927. doi: 10.1016/j.ultrasmedbio.2004.04.006
Saarakkala, Simo, Töyräs, Juha, Hirvonen, Jani, Laasanen, Mikko S., Lappalainen, Reijo and Jurvelin, Jukka S. (2004). Ultrasonic quantitation of superficial degradation of articular cartilage. Ultrasound in Medicine and Biology, 30 (6), 783-792. doi: 10.1016/j.ultrasmedbio.2004.03.005
Nissi, M. J., Töyräs, J., Laasanen, M. S., Rieppo, J., Saarakkala, S., Lappalainen, R., Jurvelin, J. S. and Nieminen, M. T. (2004). Proteoglycan and collagen sensitive MRI evaluation of normal and degenerated articular cartilage. Journal of Orthopaedic Research, 22 (3), 557-564. doi: 10.1016/j.orthres.2003.09.008
Nieminen, Heikki J., Saarakkala, Simo, Laasanen, Mikko S., Hirvonen, Jani, Jurvelin, Jukka S. and Töyräs, Juha (2004). Ultrasound attenuation in normal and spontaneously degenerated articular cartilage. Ultrasound in Medicine and Biology, 30 (4), 493-500. doi: 10.1016/j.ultrasmedbio.2003.12.007
Nieminen, Miika T., Töyräs, Juha, Laasanen, Mikko S., Silvennoinen, Johanna, Helminen, Heikki J. and Jurvelin, Jukka S. (2004). Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging. Journal of Biomechanics, 37 (3), 321-328. doi: 10.1016/S0021-9290(03)00291-4
Rieppo, Jarno, Töyräs, Juha, Nieminen, Miika T., Kovanen, Vuokko, Hyttinen, Mika M., Korhonen, Rami K., Jurvelin, Jukka S. and Helminen, Heikki J. (2003). Structure-function relationships in enzymatically modified articular cartilage. Cells Tissues Organs, 175 (3), 121-132. doi: 10.1159/000074628
Korhonen, Rami K., Laasanen, Mikko S., Töyräs, Juha, Lappalainen, Reijo, Helminen, Heikki J. and Jurvelin, Jukka S. (2003). Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage. Journal of Biomechanics, 36 (9), 1373-1379. doi: 10.1016/S0021-9290(03)00069-1
Laasanen, Mikko S., Saarakkala, Simo, Töyräs, Juha, Hirvonen, Jani, Rieppo, Jarno, Korhonen, Rami K. and Jurvelin, Jukka S. (2003). Ultrasound indentation of bovine knee articular cartilage in situ. Journal of Biomechanics, 36 (9), 1259-1267. doi: 10.1016/S0021-9290(03)00163-5
Saarakkala, S., Laasanen, M. S., Jurvelin, J. S., Törrönen, K., Lammi, M. J., Lappalainen, R. and Töyräs, J. (2003). Ultrasound indentation of normal and spontaneously degenerated bovine articular cartilage. Osteoarthritis and Cartilage, 11 (9), 697-705. doi: 10.1016/S1063-4584(03)00154-7
Hakulinen, M. A., Saarakkala, S., Töyräs, J., Kröger, H. and Jurvelin, J. S. (2003). Dual energy x-ray laser measurement of calcaneal bone mineral density. Physics in Medicine and Biology, 48 (12), 1741-1752. doi: 10.1088/0031-9155/48/12/305
Korhonen, Rami K., Saarakkala, Simo, Töyräs, Juha, Laasanen, Mikko S., Kiviranta, Ilkka and Jurvelin, Jukka S. (2003). Experimental and numerical validation for the novel configuration of an arthroscopic indentation instrument. Physics in Medicine and Biology, 48 (11), 1565-1576. doi: 10.1088/0031-9155/48/11/306
Sierpowska, Joanna, Töyräs, J., Hakulinen, M. A., Saarakkala, S., Jurvelin, J. S. and Lappalainen, R. (2003). Electrical and dielectric properties of bovine trabecular bone - Relationships with mechanical properties and mineral density. Physics in Medicine and Biology, 48 (6), 775-786. doi: 10.1088/0031-9155/48/6/306
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Korhonen, R. K., Laasanen, M. S., Töyräs, J., Rieppo, J., Hirvonen, J., Helminen, H. J. and Jurvelin, J. S. (2002). Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation. Journal of Biomechanics, 35 (7), 903-909. doi: 10.1016/S0021-9290(02)00052-0
Nieminen, Heikki J., Töyräs, Juha, Rieppo, Jarno, Nieminen, Miika T., Hirvonen, Jani, Korhonen, Rami and Jurvelin, Jukka S. (2002). Real-time ultrasound analysis of articular cartilage degradation in vitro. Ultrasound in Medicine and Biology, 28 (4), 519-525. doi: 10.1016/S0301-5629(02)00480-5
Nieminen, Miika T., Rieppo, Jarno, Töyräs, Juha, Hakumäki, Juhana M., Silvennoinen, Johanna, Hyttinen, Mika M., Helminen, Heikki J. and Jurvelin, Jukka S. (2001). T2 relaxation reveals spatial collagen architecture in articular cartilage: A comparative quantitative MRI and polarized light microscopic study. Magnetic Resonance in Medicine, 46 (3), 487-493. doi: 10.1002/mrm.1218
Hyttinen, M. M., Töyräs, J., Lapveteläinen, T., Lindblom, J., Prockop, D. J., Li, S. W., Arita, M., Jurvelin, J. S. and Helminen, H. J. (2001). Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer. Annals of the Rheumatic Diseases, 60 (3), 262-268. doi: 10.1136/ard.60.3.262
Töyräs, J., Lyyra-Laitinen, T., Niinimäki, M., Lindgren, R., Nieminen, M. T., Kiviranta, I. and Jurvelin, J. S. (2001). Estimation of the Young's modulus of articular cartilage using an arthroscopic indentation instrument and ultrasonic measurement of tissue thickness. Journal of Biomechanics, 34 (2), 251-256. doi: 10.1016/S0021-9290(00)00189-5
Nieminen, Miika T., Töyräs, Juha, Rieppo, Jarno, Hakumäki, Juhana M., Silvennoinen, Johanna, Helminen, Heikki J. and Jurvelin, Jukka S. (2000). Quantitative MR microscopy of enzymatically degraded articular cartilage. Magnetic Resonance in Medicine, 43 (5), 676-681. doi: 10.1002/(SICI)1522-2594(200005)43:5<676::AID-MRM9>3.0.CO;2-X
Töyräs, J., Kröger, H. and Jurvelin, J. S. (1999). Bone properties as estimated by mineral density, ultrasound attenuation, and velocity. Bone, 25 (6), 725-731. doi: 10.1016/S8756-3282(99)00221-5
Lyyra-Laitinen, Tiina, Niinimäki, Mia, Töyräs, Juha, Lindgren, Reijo, Kiviranta, Ilkka and Jurvelin, Jukka S. (1999). Optimization of the arthroscopic indentation instrument for the measurement of thin cartilage stiffness. Physics in Medicine and Biology, 44 (10), 2511-2524. doi: 10.1088/0031-9155/44/10/310
Töyräs, J., Rieppo, J., Nieminen, M. T., Helminen, H. J. and Jurvelin, J. S. (1999). Characterization of enzymatically induced degradation of articular cartilage using high frequency ultrasound. Physics in Medicine and Biology, 44 (11), 2723-2733. doi: 10.1088/0031-9155/44/11/303
Conference Papers
Hrubos-Strøm, H., Øverby, T.C., Sigurdardottir, F., Feng, X., Nikkonen, S., Korkalainen, H., Leppanen, T., Töyräs, J. and Arnardottir, E.S. (2024). Comparing novel electrophysiological biomarkers and circulating cardiac biomarkers in predicting cardiovascular mortality and all-cause mortality in the Akershus Sleep Apnea (ASAP) epidemiological cohort. 17th World Sleep Congress, Rio de Janeiro, Brazil, 20-25 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.sleep.2023.11.910
Väätäinen, S., Soini, E. and Töyräs, J. (2023). Should Hospitals Do Contract Research? Costs, Net Monetary Benefit, and Return on Public Sector Investments in Research at Kuopio University Hospital. ISPOR Europe 2023, Copenhagen, Denmark, 11-15 November 2023. New York, NY United States: Elsevier. doi: 10.1016/j.jval.2023.09.562
Staykov, Eric, Mann, Dwayne L, Kainulainen, Samu, Duce, Brett, Leppanen, Timo, Toyras, Juha, Sands, Scott A. and Terrill, Philip I. (2023). Nasal pressure derived airflow limitation and ventilation measurements are resilient to reduced signal quality. 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Sydney, Australia, 24-27 July 2023. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/embc40787.2023.10340215
Paakkari, P., Inkinen, S. I., Jantti, J., Tuppurainen, J., Fugazzola, M. C., Joenathan, A., Ylisiurua, S., Nieminen, M. T., Grinstaff, M. W., Kroger, H., Toyras, J., Honkanen, J. T. and Makela, J. T. (2023). TANTALUM AND IODINE BASED DUAL-CONTRAST PHOTONCOUNTING COMPUTED TOMOGRAPHY METHOD FOR ASSESSMENT OF ARTICULAR CARTILAGE COMPOSITION. World Congress of Osteoarthritis Research Society International (OARSI), Denver Co, Mar 17-20, 2023. OXFORD: ELSEVIER SCI LTD.
Orava, H., Paakkari, P., Jantti, J., Honkanen, M. K., Honkanen, J. T., Viren, T., Tanska, P., Korhonen, R. K., Grinstaff, M. W., Toyras, J. and Makela, J. T. (2023). TRIPLE CONTRAST COMPUTED TOMOGRAPHY REVEALS SITESPECIFIC DIFFERENCES IN HUMAN KNEE JOINT BIOMECHANICAL PROPERTIES. World Congress of Osteoarthritis Research Society International (OARSI), Denver Co, Mar 17-20, 2023. OXFORD: ELSEVIER SCI LTD.
Jantti, J., Joenathan, A., Honkanen, J. T., Snyder, B. D., Toyras, J., Grinstaff, M. W., Matikka, H. and Makela, J. T. (2023). TANTALUM OXIDE NANOPARTICLES FOR CONTRAST-ENHANCED COMPUTED TOMOGRAPHY DIAGNOSIS OF OSTEOARTHRITIS. World Congress of Osteoarthritis Research Society International (OARSI), Denver Co, Mar 17-20, 2023. OXFORD: ELSEVIER SCI LTD.
Orava, H., Paakkari, P., Jäntti, J., Honkanen, M.K., Honkanen, J.T., Virén, T., Tanska, P., Korhonen, R.K., Grinstaff, M.W., Töyräs, J. and Mäkelä, J.T. (2023). Triple Contrast Computed Tomography Reveals Site-Specific Differences In Human Knee Joint Biomechanical Properties. 2023 OARSI World Congress on Osteoarthritis, Denver, CO United States, 17-20 March 2023. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2023.01.263
Jäntti, J., Joenathan, A., Honkanen, J.T., Snyder, B.D., Töyräs, J., Grinstaff, M.W., Matikka, H. and Mäkelä, J.T. (2023). Tantalum Oxide Nanoparticles For Contrast-Enhanced Computed Tomography Diagnosis Of Osteoarthritis. 2023 OARSI World Congress on Osteoarthritis, Denver, CO United States, 17-20 March 2023. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2023.01.262
Paakkari, P., Inkinen, S.I., Jäntti, J., Tuppurainen, J., Fugazzola, M.C., Joenathan, A., Ylisiurua, S., Nieminen, M.T., Grinstaff, M.W., Kröger, H., Töyräs, J., Honkanen, J.T. and Mäkelä, J.T. (2023). Tantalum And Iodine Based Dual-Contrast Photon-Counting Computed Tomography Method For Assessment Of Articular Cartilage Composition. 2023 OARSI World Congress on Osteoarthritis, Denver, CO United States, 17-20 March 2023. London, United Kingdom: Elsevier. doi: 10.1016/j.joca.2023.01.278
Biedebach, Luka, Rusanen, Matias, Pórðarson, Benedikt Hólm, Arnardóttir, Erna Sif, Óskarsdóttir, María, Nikkonen, Sami, Korkalainen, Henri, Myllymaa, Sami, Töyräs, Juha, Kainulainen, Samu, Leppänen, Timo and Islind, Anna Sigridur (2023). Towards a deeper understanding of sleep stages through their representation in the latent space of variational autoencoders. 56th Annual Hawaii International Conference on System Sciences, HICSS 2023, Online, 3 - 6 January 2023. Washington, DC United States: IEEE Computer Society. doi: 10.24251/hicss.2023.382
Pala, Swetha, Nykänen, Olli, Hänninen, Nina, Mohammadi, Ali, Ebrahimi, Mohammadhossein, Moller, Nikae te, Brommer, Harold, van Weeren, P René, Mäkelä, Janne, Korhonen, Rami, Töyräs, Juha, Mikkonen, Santtu and Nissi, Mikko (2023). 3-D T1 relaxation time measurements in an equine model of mild post-traumatic osteoarthritis using MB-SWIFT. Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31st Annual Meeting, London, United Kingdom, 7-12 May 2022. Berkeley, CA United States: International Society for Magnetic Resonance in Medicine. doi: 10.58530/2022/2305
Leino, A., Korkalainen, H., Kalevo, L., Nikkonen, S., Kainulainen, S., Ryan, A., Duce, B., Sipila, K., Ahlberg, J., Sahlman, J., Miettinen, T., Westeren-Punnonen, S., Mervaala, E., Toyras, J., Myllymaa, S., Leppanen, T. and Myllymaa, K. (2022). DEEP LEARNING ENABLES ACCURATE AUTOMATIC SLEEP STAGING BASED ON AMBULATORY FOREHEAD EEG. AMSTERDAM: ELSEVIER.
Pitkanen, H., Duce, B., Leppanen, T., Kainulainen, S., Kulkas, A., Myllymaa, S., Toyras, J. and Korkalainen, H. (2022). ABSOLUTE GAMMA POWER OF EEG AROUSAL IS MODULATED BY RESPIRATORY EVENT TYPE AND SEVERITY IN OSA. AMSTERDAM: ELSEVIER.
Staykov, E., Mann, D., Duce, B., Kainulainen, S., Leppänen, T., Töyräs, J., Sands, S. and Terrill, P. (2022). P116 Increased airflow limitation during nocturnal respiratory events is associated with increased psychomotor vigilance task lapses in obstructive sleep apnoea patients. 2022 Australasian Sleep Association, Brisbane, QLD Australia, 8-11 November 2022. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/sleepadvances/zpac029.185
Chen, X., Korkalainen, H., Kainulainen, S., Leppänen, T., Oksenberg, A., Töyräs, J. and Terrill, P. (2022). Sleep architecture differs for individuals manifesting excessive daytime sleepiness with and without obstructive sleep apnea. 33rd Annual Scientific Meeting of the Australasian Sleep Association and the Australia and New Zealand Sleep Science Association, Brisbane, QLD, Australia, 8-11 November 2022. Oxford, United Kingdom: Oxford University Press . doi: 10.1093/sleepadvances/zpac029.028
Mazzotti, D. R., Leppanen, T., Sands, S., Toyras, J., Wellman, A., Kulkas, A., Redline, S., Karhu, T. and Azarbarzin, A. (2020). HYPOXEMIA DURING SLEEP DISORDERED BREATHING AND CARDIOVASCULAR DISEASE: A COMPARISON OF DIFFERENT OXYGEN DESATURATION MEASURES. 34th Annual Meeting of the Associated-Professional-Sleep-Societies (SLEEP), Philadelphia Pa, Jun 13-17, 2020. CARY: OXFORD UNIV PRESS INC.
Kainulainen, S., Toyras, J., Oksenberg, A., Korkalainen, H., Afara, I., Leino, A., Kalevo, L., Nikkonen, S., Gadoth, N., Kulkas, A., Myllymaa, S. and Leppanen, T. (2019). Differentiating Sleepy and non-sleepy obstructive sleep apnea patients using nocturnal pulse oximetry and deep learning. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.508
Nikkonen, S., Afara, I., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Artificial neural network analysis of blood oxygen saturation signal enables accurate automatic screening of sleep apnea. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.624
Korkalainen, H., Aakko, J., Nikkonen, S., Kainulainen, S., Leino, A., Duce, B., Afara, I. O., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Deep learning enables accurate sleep staging based on a single frontal EEG channel. 15th World Sleep Congress, World Sleep 2019, Vancouver, Canada, 20-25 September, 2019 . Amsterdam, Netherlands: Elsevier BV.
Ala-Myllymäki, Juho, Paakkonen, Tommi, Töyräsa, Juha and Afara, Isaac O. (2019). Arthroscopic near-infrared spectroscopic prediction of human meniscus properties. Bio-Optics: Design and Application 2019, Tucson, AZ, United States, 14–17 April 2019. Washington, D.C.: Optical Society of America (OSA). doi: 10.1364/BODA.2019.JT4A.35
Virtanen, V. K., Nippolainen, E., Shaikh, R., Afara, I., Toyras, J., Saarakkala, S. and Rieppo, L. (2019). Detection of enzymatically and mechanically induced degradation of bovine articular cartilage tissue with mid-infrared spectroscopy. OARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis, Toronto, Canada, 2-5 May 2019. Oxford, United Kingdom: Elsevier . doi: 10.1016/j.joca.2019.02.035
Shaikh, Rubina, Nippolainen, Ervin, Virtanen, Vesa, Rieppo, Lassi, Haas, Julian, Mizaikoff, Boris, Artyushenko, Viacheslav, Bibikova, Olga, Afara, Isaac, Saarakkala, Simo and Töyräs, Juha (2019). Mid-infrared spectroscopic assessment of cartilage degeneration. Biophotonics Congress, Tucson, AZ, United States, 14–17 April 2019. Washington, D.C.: Optical Society of America (OSA). doi: 10.1364/BODA.2019.DS1A.3
Nippolainen, Ervin, Shaikh, Rubina, Virtanen, Vesa, Rieppo, Lassi, Afara, Isaac, Saarakkala, Simo and Töyräs, Juha (2019). Mid-infrared and near infrared spectroscopic analysis of mechanically and enzymatically damaged cartilage. Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), Tucson, AZ USA, 14-17 April 2019. Washington, DC USA: Optical Society of America. doi: 10.1364/BODA.2019.JT4A.37
Torniainen, Jari, Afara, Isaac O., Prakash, Mithilesh, Sarin, Jaakko K., Stenroth, Lauri and Töyräs, Juha (2019). Automated preprocessing of near infrared spectroscopic data. Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), Tucson, AZ, United States, 14-17 April 2019. Washington, DC, United States: Optical Society of America. doi: 10.1364/BODA.2019.DS2A.6
Afara, Isaac O., Sarin, Jaakko K., Ojanen, Simo, Finnila, Mikko, Herzog, Walter, Saarakkala, Simo, Korhonen, Rami K. and To¨yräs, Juha (2018). Deep learning classification of cartilage integrity using near infrared spectroscopy. Clinical and Translational Biophotonics, TRANSLATIONAL 2018, Hollywood, FL United States, 3-6 April 2018. Washington, DC United States: The Optical Society. doi: 10.1364/TRANSLATIONAL.2018.JTu3A.27
Torniainen, Jari E., Ristaniemi, Aapo, Stenroth, Lauri and To¨yräs, Juha (2018). Estimating mechanical properties of bovine knee ligaments and tendons with near infrared spectroscopy. Clinical and Translational Biophotonics, TRANSLATIONAL 2018, Hollywood, FL United States, 3-6 April 2018. Washington, DC United States: The Optical Society. doi: 10.1364/TRANSLATIONAL.2018.JW3A.29
Ala-Myllymäki, Juho, To¨yräs, Juha and Afara, Isaac O. (2018). Near-infrared spectroscopy: A potential tool for mapping meniscus properties. Clinical and Translational Biophotonics, TRANSLATIONAL 2018, Hollywood, FL United States, 3-6 April 2018. Washington, DC United States: The Optical Society. doi: 10.1364/TRANSLATIONAL.2018.JW3A.38
Kulkas, Antti, Nikkonen, Sami, Töyräs, Juha, Mervaala, Esa and Leppänen, Timo (2018). Simulation of required CPAP usage to normalize AHI in obstructive sleep apnea patients. World Congress on Medical Physics and Biomedical Engineering (2018), Prague, Czech Republic, 3-8 June 8 2018. New York, NY, United States: Springer. doi: 10.1007/978-981-10-9038-7_23
Sarin, Jaakko K., te Moller, Nikae, Brommer, Harold, van Weeren, Rene´, Mancini, Irina, Malda, Jos, Afara, Isaac O. and Töyräs, Juha (2018). Spectroscopic evaluation of post-traumatic osteoarthritis in Shetland ponies. Optical Tomography and Spectroscopy (OTS 2018), Hollywood, FL, United States, 3-6 April 2018. Washington, D.C.: OSA - The Optical Society. doi: 10.1364/OTS.2018.OTu4D.5
Prakash, Mithilesh, Joukainen, Antti, Sarin, Jaakko, Rieppo, Lassi, Afara, Isaac and Töyräs, Juha (2018). Near-infrared spectroscopy based arthroscopic evaluation of human knee joint cartilage, through automated selection of an anatomically specific regression model. Optical Tomography and Spectroscopy (OTS 2018), Hollywood, FL, United States, 3-6 April 2018. Washington, D.C.: OSA - The Optical Society. doi: 10.1364/OTS.2018.OF4D.3
Kulkas, Antti, Muraja-Murro, A., Leppänen, T., Tiihonen, P., Mervaala, E. and Töyräs, J. (2015). Desaturation event characteristics and mortality risk in severe sleep apnea. World Congress on Medical Physics and Biomedical Engineering (2015), Toronto, ON, Canada, 7-12 June 2015. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-19387-8_231
Kulkas, A., Tiihonen, P., Julkunen, P., Mervaala, E. and Töyräs, J. (2013). Desaturation delay, parameter for evaluating severity of sleep disordered breathing. World Congress on Medical Physics and Biomedical Engineering, Beijing, China, 2 -31 May 2012. Heidelberg, Germany: Springer. doi: 10.1007/978-3-642-29305-4_90
Myllymaa, Sami, Lepola, Pasi, Hukkanen, Taina, Oun, Andre, Mervaala, Esa, Toyras, Juha, Lappalainen, Reijo and Myllymaa, Katja (2013). Novel screen printed electrode set for routine EEG recordings in patients with altered mental status. 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013, Osaka, Japan, 3-7 July 2013. Piscataway, NJ, United States: Institute of Electrical and Electronics Engineers. doi: 10.1109/EMBC.2013.6611099
Karjalainen, Janne P., Töyräs, Juha and Jurvelin, Jukka S. (2010). Cepstrum method enables accurate assessment of thickness of cortical bone layers - Potential improvement for analysis of ultrasound backscatter from underlying trabecular matrix. 20th International Congress on Acoustics 2010, ICA 2010 - Incorporating the 2010 Annual Conference of the Australian Acoustical Society, , , August 23, 2010-August 27, 2010.
Pulkkinen, H., Tiitu, V., Valonen, P., Silvast, T. S., Jurvelin, J. S., Töyräs, J., Kiviranta, I. and Lammi, M. J. (2010). Repair of osteochondral defects with recombinant human type II collagen gel and autologous chondrocytes in a rabbit model. AO Research Institute Davos.
Karjalainen, J., Töyräs, J., Riekkinen, O. and Hakulinen, M. A. (2009). Ultrasound backscattering outperforms the clinically used ultrasound parameters in discrimination of osteoporotic-like human trabecular bone samples. World Congress on Medical Physics and Biomedical Engineering: Diagnostic Imaging, , , September 7, 2009-September 12, 2009. Springer Verlag. doi: 10.1007/978-3-642-03879-2-27
Sierpowska, J., Hakulinen, M. A., Töyräs, J., Day, J. S., Weinans, H., Jurvelin, J. S. and Lappalainen, R. (2005). Prediction of mechanical properties of human trabecular bone by electrical measurements. doi: 10.1088/0967-3334/26/2/012
Koistinen, A., Santavirta, S. S., Kröger, H., Töyräs, J. and Lappalainen, R. (2004). Effect of bone mineral density on bone screw insertion torque - A study with peripheral quantitative computed tomography (pQCT) and human femoral bone. Transactions - 7th World Biomaterials Congress, , , May 17, 2004-May 21, 2004.
Laasanen, Mikko S., Töyräs, Juha, Vasara, Anna I., Hyttinen, Mika M., Saarakkala, Simo, Hirvonen, Jani, Jurvelin, Jukka S. and Kiviranta, Ilkka (2003). Mechano-acoustic diagnostic of cartilage degeneration and repair. Journal of Bone and Joint Surgery Inc.. doi: 10.2106/00004623-200300002-00010